{"id":"W2089365658","doi":"10.1016/j.pep.2014.12.008","title":"Preparation and characterization of human ADCK3, a putative atypical kinase","year":2014,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Coenzyme Q10 studies and effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biochemistry; Maltose-binding protein; Protein kinase domain; Fusion protein; Kinase; Protein kinase A; Biology; Ubiquinol; Recombinant DNA; Cell biology; Gene; Mitochondrion; Coenzyme Q – cytochrome c reductase; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001307529,0.00006921628,0.00007809588,0.00002072975,0.00009582528,0.00001223898,0.00002799506,0.00006552943,0.000003522475],"category_scores_gemma":[0.00005230377,0.00005986352,0.00001373205,0.00002871047,0.00004785553,0.000006717581,0.00003870566,0.00002869916,6.694291e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000021968,"about_ca_system_score_gemma":0.000004706512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003189447,"about_ca_topic_score_gemma":0.000001321296,"domain_scores_codex":[0.9994833,0.00008421757,0.0001215605,0.0001900424,0.00005778651,0.00006310923],"domain_scores_gemma":[0.9996971,0.000006007398,0.0000976175,0.0001127896,0.00005171734,0.00003476011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001230758,0.00002861242,0.0003392924,0.000040901,0.000003647682,3.198048e-8,0.000179155,4.32886e-7,0.9954066,0.0004386728,0.0001024008,0.003337219],"study_design_scores_gemma":[0.0003105344,0.000332373,0.02215602,0.00003808766,0.000005295258,7.650592e-7,0.0000235989,0.00025918,0.9726809,0.0001367878,0.003983023,0.00007345288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945392,0.0001493915,0.00475723,0.0001111865,0.00001448076,0.0003389726,0.000004680709,0.000006823018,0.00007800508],"genre_scores_gemma":[0.9991162,0.00006009487,0.0003352309,0.00002286131,0.00006907849,0.00008669658,0.0001582061,0.000005859495,0.0001457737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02272568,"threshold_uncertainty_score":0.2441164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008341052051325216,"score_gpt":0.2701183713362313,"score_spread":0.2617773192849061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}