{"id":"W2089383316","doi":"10.1038/mt.2009.240","title":"Tomorrow, Interrupted?: Risk, Ethics, and Medical Advance in Gene Transfer","year":2009,"lang":"en","type":"letter","venue":"Molecular Therapy","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Gene transfer; Biology; Computational biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001117018,0.0003332309,0.0005748447,0.0002295479,0.00006107685,0.00002051421,0.0001719379,0.003508719,0.0002209941],"category_scores_gemma":[0.0001606821,0.0002575246,0.0001654704,0.0002089505,0.0006409906,0.00003085433,0.00002089662,0.009747174,0.000008828508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006042037,"about_ca_system_score_gemma":0.0002777447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001124054,"about_ca_topic_score_gemma":0.00003017136,"domain_scores_codex":[0.9969459,0.0004922557,0.0004433659,0.0005508047,0.001209487,0.0003582482],"domain_scores_gemma":[0.9991099,0.0001593386,0.0000610507,0.000393351,0.00009382476,0.0001825548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009010218,0.000595533,0.0003549132,0.0008379327,0.0006649646,0.01973668,0.004430334,0.000007266132,0.02011064,0.0008094265,0.05158313,0.8999681],"study_design_scores_gemma":[0.004549566,0.0006840758,0.001796784,0.001026979,0.00007564614,0.0002972411,0.00001445802,0.0003877955,0.005866844,0.004370828,0.9804261,0.000503698],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.02001753,0.01304753,0.009593206,0.9562508,0.0002443208,0.0004921086,0.00001316455,0.00005227486,0.0002890271],"genre_scores_gemma":[0.05389171,0.02766902,0.0007394999,0.9160142,0.0009318461,0.00002246404,0.0003447346,0.00007633557,0.0003101844],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.928843,"threshold_uncertainty_score":0.9999877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02171219739339391,"score_gpt":0.3146829887578195,"score_spread":0.2929707913644256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}