{"id":"W2089408255","doi":"10.1007/s12272-001-1202-9","title":"5-Methoxy-8-(2-hydroxy-3-buthoxy-3-methylbutyloxy)-psoralen isolated from Angelica dahurica inhibits cyclooxygenase-2 and 5-Lipoxygenase in mouse bone marrow-derived mast cells","year":2008,"lang":"en","type":"article","venue":"Archives of Pharmacal Research","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Psoralen; Cyclooxygenase; Chemistry; Arachidonate 5-lipoxygenase; Degranulation; Prostaglandin D2; Pharmacology; Lipoxygenase; Bone marrow; Western blot; Blot; Prostaglandin; Enzyme; Biochemistry; Biology; Immunology; Receptor; Arachidonic acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009965103,0.0005119726,0.0003709246,0.0003370397,0.0001610199,0.000169633,0.0002552713,0.000331068,0.002190363],"category_scores_gemma":[0.00008962787,0.0002117032,0.0003199226,0.0001456327,0.0002394913,0.0003491913,0.0001663657,0.0005626713,0.0006087338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007943487,"about_ca_system_score_gemma":0.0002179838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000307898,"about_ca_topic_score_gemma":0.0005214742,"domain_scores_codex":[0.9999459,0.000007908136,0.000005222598,0.00000750576,0.00001016232,0.00002328071],"domain_scores_gemma":[0.9999191,0.00001481677,0.00002613175,0.000007838858,0.000005381617,0.00002685641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006113598,0.00009589267,0.0001658119,0.00007308262,0.00001404706,0.0001637108,0.00001608263,0.0000615049,0.9959515,0.00006772523,0.00002814259,0.002751177],"study_design_scores_gemma":[0.0002358026,0.003828132,0.007018429,0.00001497976,0.00007229215,0.0005026279,0.00004267377,0.0004203694,0.9861332,0.00006231384,0.001658662,0.0000105848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911684,0.004409256,0.001976672,0.0001685905,0.0001141003,0.00004419111,0.000182006,0.00007903487,0.001857615],"genre_scores_gemma":[0.9942642,0.001990666,0.001013672,0.00007342487,0.0000787942,0.00001664775,0.0003041833,0.00001022096,0.002248204],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002190363,"threshold_uncertainty_score":0.007327437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04854696919210171,"score_gpt":0.3411280719079568,"score_spread":0.2925811027158551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}