{"id":"W2089507736","doi":"10.1165/rcmb.2013-0369oc","title":"Fibroblast Signal Transducer and Activator of Transcription 4 Drives Cigarette Smoke–Induced Airway Fibrosis","year":2014,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Cigarette smoke; Airway; Fibroblast; Activator (genetics); Transcription (linguistics); Fibroblast growth factor; Fibrosis; Medicine; STAT protein; Chemistry; Internal medicine; Biology; Cell biology; Acoustics; Physics; Signal transduction; Surgery; STAT3; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003391357,0.0007863423,0.0004292017,0.0007160516,0.0003338996,0.0005105593,0.0005176767,0.0008490955,0.003991747],"category_scores_gemma":[0.0002116066,0.0004941461,0.00074673,0.0004018777,0.0006374968,0.0002898821,0.0004411299,0.001810041,0.00115235],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005965124,"about_ca_system_score_gemma":0.0005231318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001288878,"about_ca_topic_score_gemma":0.002709717,"domain_scores_codex":[0.9991811,0.0001209491,0.00009936399,0.000139366,0.0002682071,0.0001909484],"domain_scores_gemma":[0.9995021,0.00009346274,0.0001473445,0.00005604302,0.00003554119,0.0001655587],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000120296,0.00007780922,0.0002512671,0.0000325968,0.000004492796,0.00006637272,0.00001649363,0.00004389765,0.9988388,0.00008552177,0.00005450676,0.0004078842],"study_design_scores_gemma":[0.00007820888,0.000543708,0.009517635,0.00002261704,0.00003339328,0.0005179161,0.0001318017,0.002084302,0.9835391,0.0001288389,0.003387952,0.00001452974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906071,0.001130176,0.003330547,0.0004818222,0.0001987653,0.000130709,0.001609492,0.0002432788,0.002267972],"genre_scores_gemma":[0.9808564,0.001173311,0.00458231,0.0003139435,0.00004272084,0.0002178421,0.002314664,0.0001115237,0.01038738],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003991747,"threshold_uncertainty_score":0.01335377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01088975291138451,"score_gpt":0.2670247104630822,"score_spread":0.2561349575516977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}