{"id":"W2089512600","doi":"10.1093/nar/gkn103","title":"Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster","year":2008,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Trace Elements in Health","field":"Nursing","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of General Medical Sciences; Université de Sherbrooke; European Commission; University of Oxford; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; National Institutes of Health; National Science Foundation","keywords":"Biology; Cysteine; Drosophila melanogaster; Metallothionein; Copper; Mutant; Transcription factor; Homology (biology); Genetics; Caenorhabditis elegans; Schneider 2 cells; Biochemistry; Cell biology; Amino acid; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004128257,0.0002999613,0.0001204643,0.0001051621,0.0001244048,0.0001501578,0.0001433039,0.0001415301,0.0007866214],"category_scores_gemma":[0.00007085752,0.00007369029,0.0001780318,0.00005540116,0.0001201436,0.00008806855,0.000144453,0.0002051039,0.0003579844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004648813,"about_ca_system_score_gemma":0.0001171093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008415815,"about_ca_topic_score_gemma":0.001272048,"domain_scores_codex":[0.9999448,0.000004607503,0.000003109127,0.00002263933,0.0000134377,0.00001135749],"domain_scores_gemma":[0.9999505,0.000005661286,0.00001480342,0.000005257088,0.000008047667,0.00001567871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003975571,0.000004773039,0.0003025642,0.00001617454,0.000001372764,0.00002269391,0.000006549968,0.00003006085,0.9987724,0.00004574186,0.00003483936,0.0007229385],"study_design_scores_gemma":[0.00001496104,0.00009334925,0.01390959,0.00000653847,0.000007380418,0.0002618084,0.00002529565,0.001558834,0.9807749,0.00006523387,0.003276159,0.000005969097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994557,0.0009993997,0.002789991,0.00005464481,0.00001853031,0.00001094257,0.0003436216,0.0001264148,0.001099408],"genre_scores_gemma":[0.9946016,0.0002939379,0.001922904,0.0000349485,0.000005061278,0.0000148437,0.0007217815,0.00001731919,0.002387534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008415815,"threshold_uncertainty_score":0.003373027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07519653026801865,"score_gpt":0.3533554100037209,"score_spread":0.2781588797357023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}