{"id":"W2089512600","doi":"10.1093/nar/gkn103","title":"Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster","year":2008,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Trace Elements in Health","field":"Nursing","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institute of General Medical Sciences; Université de Sherbrooke; European Commission; University of Oxford; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; National Institutes of Health; National Science Foundation","keywords":"Biology; Cysteine; Drosophila melanogaster; Metallothionein; Copper; Mutant; Transcription factor; Homology (biology); Genetics; Caenorhabditis elegans; Schneider 2 cells; Biochemistry; Cell biology; Amino acid; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001408123,0.0003022267,0.0004855737,0.0006827362,0.0007158212,0.00004747826,0.0003346145,0.0003915347,0.001258006],"category_scores_gemma":[0.0005475645,0.0002994304,0.0001796055,0.001135071,0.0007000277,0.0004940303,0.00007293397,0.001269344,0.0004071277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004873958,"about_ca_system_score_gemma":0.0001355668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003489145,"about_ca_topic_score_gemma":0.00003543484,"domain_scores_codex":[0.9941081,0.001234349,0.0007358513,0.0006898962,0.002165527,0.001066243],"domain_scores_gemma":[0.9974554,0.0007024306,0.0001500995,0.0006506412,0.0007353264,0.0003060673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004113738,0.000315448,0.00285645,0.0001891625,0.0001191196,0.00001803682,0.009265032,0.000007115862,0.9043429,0.00002669136,0.06287448,0.01587178],"study_design_scores_gemma":[0.01729981,0.01035828,0.2268473,0.0007520553,0.0002864994,0.0002412387,0.009472761,0.00932098,0.4519996,0.001036035,0.2701882,0.0021972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902178,0.0003942184,0.0001158481,0.005912006,0.0007590876,0.001005444,0.0002065773,0.0001608992,0.001228086],"genre_scores_gemma":[0.9972058,0.0001485713,0.0006053709,0.0009290358,0.0001927501,0.00001046073,0.00005662983,0.0001278893,0.0007235056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4523433,"threshold_uncertainty_score":0.9999458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07519653026801865,"score_gpt":0.3533554100037209,"score_spread":0.2781588797357023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}