{"id":"W2089539551","doi":"10.1186/1752-0509-7-87","title":"Modularity and evolutionary constraints in a baculovirus gene regulatory network","year":2013,"lang":"en","type":"article","venue":"BMC Systems Biology","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; CancerCare Manitoba Foundation","keywords":"Biology; ORFS; Genetics; Gene; Genome; Gene regulatory network; Computational biology; Systems biology; Open reading frame; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005890389,0.0002207027,0.0004688438,0.001583184,0.000570194,0.0009355347,0.0006452344,0.0005002031,0.0007160628],"category_scores_gemma":[0.004339472,0.0003102527,0.0004306536,0.0008649642,0.001034253,0.001018064,0.0005243479,0.0003489368,0.0001182245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008076232,"about_ca_system_score_gemma":0.0004120939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001245849,"about_ca_topic_score_gemma":0.001242969,"domain_scores_codex":[0.999477,0.0001160098,0.00002535546,0.0002303817,0.00009733081,0.0000539909],"domain_scores_gemma":[0.9969233,0.001654142,0.0007544173,0.0001662107,0.0002484717,0.0002534869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007104811,0.0001920061,0.1729553,0.00086845,0.0004994195,0.002004735,0.001794393,0.3496825,0.3174528,0.09247288,0.000863259,0.06050386],"study_design_scores_gemma":[0.00004652955,0.0002107009,0.09680726,0.00005536091,0.000187337,0.001138565,0.0003273257,0.7779308,0.01059007,0.1095793,0.003068459,0.00005823476],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9443222,0.0003956333,0.05344712,0.0001614923,0.000004460535,0.00002824977,0.0002073636,0.0001189575,0.001314341],"genre_scores_gemma":[0.9824369,0.0001415056,0.01673708,0.00002515159,0.00001281808,0.00004092001,0.0003286286,0.00001835601,0.0002587443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583184,"threshold_uncertainty_score":0.005859792,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01113880836845419,"score_gpt":0.2396480022588915,"score_spread":0.2285091938904373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}