{"id":"W2089546540","doi":"10.1038/ajg.2009.199","title":"Clinically Meaningful Improvement in Health-Related Quality of Life in a Randomized Controlled Trial of Certolizumab Pegol Maintenance Therapy for Crohn's Disease","year":2009,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Certolizumab pegol; Medicine; Placebo; Quality of life (healthcare); Maintenance therapy; Randomized controlled trial; Physical therapy; Visual analogue scale; Crohn's disease; Internal medicine; EQ-5D; Disease; Health related quality of life; Alternative medicine; Infliximab; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003265968,0.00101442,0.003478209,0.0004441557,0.0004835194,0.00109867,0.0007378521,0.001841611,0.004016213],"category_scores_gemma":[0.004277885,0.0005982555,0.001917643,0.0003931835,0.001134522,0.0007560898,0.0004352084,0.002158963,0.000313375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006498574,"about_ca_system_score_gemma":0.001000453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006420268,"about_ca_topic_score_gemma":0.001130586,"domain_scores_codex":[0.9973682,0.001683176,0.0002432012,0.0003275447,0.000200425,0.0001773973],"domain_scores_gemma":[0.9978282,0.0008676315,0.0007083387,0.0001207736,0.0001071813,0.0003679136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9877033,0.002129021,0.0007384008,0.0005186125,0.001063456,0.00002215927,0.0000254951,0.0001052139,0.000850209,0.00003745596,0.0001825431,0.00662404],"study_design_scores_gemma":[0.9684945,0.02766656,0.002591122,0.00003849481,0.0005895091,0.0000163915,0.000009754486,0.0002294282,0.000153154,0.00004016807,0.0001644179,0.000006448533],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841639,0.009045646,0.0005719687,0.0007072439,0.0006912781,0.003122607,0.0004708273,0.00009666417,0.001129907],"genre_scores_gemma":[0.9913139,0.0018184,0.001083104,0.0005840448,0.0004160072,0.003808506,0.0004045487,0.000008453523,0.0005631183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004016213,"threshold_uncertainty_score":0.01727229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01186619162563935,"score_gpt":0.2997754645753709,"score_spread":0.2879092729497315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}