{"id":"W2089570919","doi":"10.1371/journal.pone.0113273","title":"Escherichia coli STb Enterotoxin Dislodges Claudin-1 from Epithelial Tight Junctions","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Tight junction; Claudin; Enterotoxin; Caco-2; Enterotoxigenic Escherichia coli; Chemistry; Cytoplasm; Heat-stable enterotoxin; Biology; Molecular biology; Escherichia coli; Biochemistry; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000128696,0.0002831992,0.0003029596,0.0002232047,0.0001393533,0.0003645624,0.0001297252,0.0003626618,0.0006888434],"category_scores_gemma":[0.0001747668,0.0001679649,0.0002210036,0.0002069256,0.0001253293,0.0002852978,0.0003294393,0.0005949799,0.0003289742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002268378,"about_ca_system_score_gemma":0.0001433447,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005725073,"about_ca_topic_score_gemma":0.0006985435,"domain_scores_codex":[0.9998191,0.00002936159,0.00001475632,0.0000252762,0.00005484619,0.00005663039],"domain_scores_gemma":[0.9998453,0.00002520945,0.00004988088,0.00001966128,0.00002433879,0.00003567948],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003566514,0.000008452565,0.0001491941,0.0000238683,0.000001590341,0.0000256991,0.00001055967,0.00000904131,0.9994024,0.00001904951,0.00001554883,0.0002990424],"study_design_scores_gemma":[0.00001237634,0.0003311977,0.02405553,0.00002047478,0.0000091823,0.0003819475,0.00009028221,0.0005977322,0.9716965,0.00005237991,0.002747454,0.00000496545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953161,0.001306655,0.002309995,0.0001420179,0.00002250795,0.00001621208,0.0002306133,0.00004110497,0.0006147322],"genre_scores_gemma":[0.9929401,0.001123453,0.001968967,0.0000970031,0.000008807297,0.00001879985,0.0008863676,0.00002625424,0.002930356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006888434,"threshold_uncertainty_score":0.002304435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01938388754409869,"score_gpt":0.2203899591754696,"score_spread":0.2010060716313709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}