{"id":"W2089590932","doi":"10.1038/cdd.2015.44","title":"ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion","year":2015,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"School of Medicine, Virginia Commonwealth University; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Virginia Commonwealth University","keywords":"Ectodomain; Syncytiotrophoblast; Trophoblast; Cell biology; Cell fusion; Syncytium; Biology; Placenta; Cell; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009165108,0.0001265997,0.000253438,0.00008274722,0.00006504494,0.00001210155,0.0000332678,0.00007678445,0.00004418562],"category_scores_gemma":[0.00006299452,0.0001024292,0.00005460329,0.00009643636,0.00002869339,0.00006790887,0.00005011277,0.00007859908,0.000006201253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002319551,"about_ca_system_score_gemma":0.00002670514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004242976,"about_ca_topic_score_gemma":0.00001033912,"domain_scores_codex":[0.9992381,0.00004656229,0.0002068482,0.0001796255,0.0001746914,0.0001541516],"domain_scores_gemma":[0.9995254,0.00004150657,0.00009847907,0.0001282809,0.00008549291,0.0001208811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001273292,0.0005990635,0.6348023,0.0008908589,0.0001795325,0.00002210654,0.00328719,0.00001623482,0.3456389,0.0005594895,0.00160755,0.01112354],"study_design_scores_gemma":[0.004672063,0.0005490778,0.8792233,0.0003818916,0.0003050971,0.00001537915,0.0004295844,0.003888573,0.1085802,0.001393075,0.0003355098,0.0002262847],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898921,0.003372451,0.001139789,0.00005145426,0.0001481173,0.0001978691,0.000006400478,0.00007423531,0.005117586],"genre_scores_gemma":[0.9980386,0.0004671559,0.0008813822,0.00002228038,0.00005417086,0.000008940282,0.00007312886,0.00001148199,0.0004428329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.244421,"threshold_uncertainty_score":0.4176942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02406763962711524,"score_gpt":0.2415195425962259,"score_spread":0.2174519029691107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}