{"id":"W2089590932","doi":"10.1038/cdd.2015.44","title":"ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion","year":2015,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"School of Medicine, Virginia Commonwealth University; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Virginia Commonwealth University","keywords":"Ectodomain; Syncytiotrophoblast; Trophoblast; Cell biology; Cell fusion; Syncytium; Biology; Placenta; Cell; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004322226,0.0002634758,0.0004266509,0.0002731315,0.0003004442,0.0004575952,0.0002419023,0.0003605134,0.002792641],"category_scores_gemma":[0.0004607163,0.0001856444,0.00046825,0.0002052435,0.0003428517,0.0003219665,0.0003285508,0.0009918384,0.0004985974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002551925,"about_ca_system_score_gemma":0.0003517941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009143005,"about_ca_topic_score_gemma":0.001185257,"domain_scores_codex":[0.9996215,0.0001258298,0.00003746657,0.00003123224,0.0000465466,0.0001374109],"domain_scores_gemma":[0.9998038,0.00007406458,0.00001707672,0.00003444129,0.00001725264,0.00005332474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002926882,0.0003895437,0.0005063805,0.00009910366,0.00002780599,0.0004610953,0.0001629587,0.0001380345,0.9908138,0.0004186645,0.0003001552,0.003755701],"study_design_scores_gemma":[0.0001512477,0.002609478,0.006828651,0.00001454189,0.0000734938,0.000711362,0.0002219589,0.0009205747,0.9844881,0.000137087,0.003834743,0.000008786208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962878,0.0008716921,0.0006915653,0.0001196087,0.00005806242,0.00002541661,0.0001066016,0.00003055315,0.001808725],"genre_scores_gemma":[0.9967028,0.0006644763,0.0003788651,0.00003461673,0.00001639141,0.00002281239,0.000192685,0.000005891191,0.001981511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002792641,"threshold_uncertainty_score":0.009342253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02406763962711524,"score_gpt":0.2415195425962259,"score_spread":0.2174519029691107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}