{"id":"W2089597096","doi":"10.1139/o05-040","title":"Epigenome programming by Polycomb and Trithorax proteins","year":2005,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epigenome; Biology; Histone; Epigenetics; Polycomb-group proteins; Transcription (linguistics); DNA methylation; RNA interference; Genetics; Methylation; PRC2; Gene; Transcription factor; Computational biology; Histone H3; RNA; Repressor; Gene expression; Philosophy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002750886,0.0005902101,0.0007926361,0.001021376,0.0001653542,0.0005679363,0.0006281162,0.0005956699,0.002618763],"category_scores_gemma":[0.0002245433,0.0001651186,0.0001582727,0.001120989,0.0002945561,0.0006592681,0.0003738915,0.0006923081,0.003021199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004616778,"about_ca_system_score_gemma":0.0003684112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006282252,"about_ca_topic_score_gemma":0.001343258,"domain_scores_codex":[0.9999278,0.00001134796,0.000007349061,0.00001498474,0.00003080685,0.000007714364],"domain_scores_gemma":[0.9999232,0.00002064997,0.00001413856,0.000003710303,0.00002373612,0.00001447861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000596396,0.00003105476,0.000211155,0.003435489,0.0000477451,0.0002713328,0.00004914249,0.0003527319,0.008289005,0.003961257,0.02325813,0.9600333],"study_design_scores_gemma":[0.0000179155,0.00005626343,0.00159077,0.0005355211,0.00003184931,0.001450917,0.00005240299,0.0001027031,0.002161884,0.002435353,0.9915534,0.00001105931],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005573567,0.9955499,0.0004400166,0.0002551925,0.0002109012,0.000005180795,0.00001801775,0.00002179599,0.002941647],"genre_scores_gemma":[0.002611486,0.9926387,0.0004780996,0.0002364026,0.0002343078,0.0000111226,0.00004664896,0.000002862409,0.003740415],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002618763,"threshold_uncertainty_score":0.008760631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684863716142742,"score_gpt":0.2937915139420836,"score_spread":0.2769428767806562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}