{"id":"W2089607336","doi":"10.1074/jbc.m707352200","title":"Thermosensing Coordinates a Cis-regulatory Module for Transcriptional Activation of the Intracellular Virulence System in Salmonella enterica Serovar Typhimurium","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Salmonella and Campylobacter epidemiology","field":"Agricultural and Biological Sciences","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; McMaster University","funders":"Canadian Institutes of Health Research; Public Health Agency; Public Health Agency of Canada; McMaster University","keywords":"Virulence; Salmonella enterica; Biology; Regulon; Microbiology; Salmonella; Gene; Operon; Intracellular; Intracellular parasite; Secretion; Regulation of gene expression; Extracellular; Virulence factor; Pathogen; Genetics; Bacteria; Mutant; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000178297,0.0003548522,0.0003136807,0.0002465481,0.0001583722,0.0002672317,0.000206752,0.00023284,0.0007740455],"category_scores_gemma":[0.000167315,0.000270458,0.0003569082,0.00008166903,0.0002782765,0.0001176815,0.0004507813,0.0004118347,0.0007943828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003226333,"about_ca_system_score_gemma":0.0002642613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006712558,"about_ca_topic_score_gemma":0.0009056738,"domain_scores_codex":[0.9997866,0.00003789228,0.00001696993,0.00006117688,0.00004979374,0.00004761622],"domain_scores_gemma":[0.9998398,0.0000252949,0.00003276508,0.00002525263,0.00002352264,0.00005336181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004449717,0.000006272483,0.0001104133,0.000007968224,7.737159e-7,0.00002196919,0.00001358937,0.00003101493,0.999357,0.0000701273,0.00001200147,0.0003242703],"study_design_scores_gemma":[0.00002111501,0.0003250812,0.009114676,0.00001182678,0.00001223992,0.0002858107,0.0000881023,0.002900511,0.9849693,0.0001621428,0.002092648,0.00001661194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878559,0.0004384785,0.009388975,0.0001057368,0.00005959387,0.00002952497,0.0001895713,0.0004417759,0.001490568],"genre_scores_gemma":[0.9920427,0.0001000444,0.005529753,0.00007379451,0.00001266009,0.00002663906,0.0002961814,0.00006902692,0.0018492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007740455,"threshold_uncertainty_score":0.002589464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02447260353196471,"score_gpt":0.2255602733677871,"score_spread":0.2010876698358224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}