{"id":"W2089717057","doi":"10.1021/ac010545r","title":"Electrochemically Induced pH Changes Resulting in Protein Unfolding in the Ion Source of an Electrospray Mass Spectrometer","year":2001,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Electrospray; Mass spectrometry; Electrospray mass spectrometry; Ion; Analytical Chemistry (journal); Chromatography; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004404139,0.000352691,0.0002042563,0.0002094761,0.0001894491,0.0003994455,0.0004400417,0.0005326645,0.0008743057],"category_scores_gemma":[0.0006121997,0.0002045951,0.0001539053,0.0002641635,0.0003211449,0.0004717467,0.0004013754,0.0005363717,0.0002310189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002960096,"about_ca_system_score_gemma":0.0001875399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002041554,"about_ca_topic_score_gemma":0.0002150743,"domain_scores_codex":[0.9997393,0.00003177642,0.00001578806,0.00006010193,0.0001219246,0.00003115904],"domain_scores_gemma":[0.9997697,0.0000756462,0.00004914882,0.00001688988,0.00005415494,0.00003451906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003786761,0.000006241155,0.00008655864,0.00001543097,0.000002834864,0.0000463677,0.00002334618,0.00003941163,0.9988117,0.00003255606,0.00002139381,0.0008762442],"study_design_scores_gemma":[0.00001137039,0.00008046288,0.001758957,0.000003569247,0.000005263754,0.0001828542,0.00001752716,0.001347865,0.9956938,0.00005715159,0.0008357609,0.000005430356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737837,0.0006995005,0.02341764,0.0001895477,0.00006006468,0.00006669364,0.0001660856,0.0003296344,0.001287155],"genre_scores_gemma":[0.9715507,0.001041928,0.02474837,0.0002348585,0.00003309938,0.0000866366,0.0003890947,0.00008867708,0.001826585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008743057,"threshold_uncertainty_score":0.00292486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01643158179775051,"score_gpt":0.2721334039050923,"score_spread":0.2557018221073418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}