{"id":"W2089796211","doi":"10.3111/13696998.2013.802239","title":"Randomized, open-label study to evaluate patient-reported outcomes with fingolimod after changing from prior disease-modifying therapy for relapsing multiple sclerosis: EPOC study rationale and design","year":2013,"lang":"en","type":"article","venue":"Journal of Medical Economics","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novartis Pharmaceuticals Corporation","keywords":"Medicine; Fingolimod; Multiple sclerosis; Randomized controlled trial; Natalizumab; Physical therapy; Disease; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004962211,0.0002905412,0.0014049,0.0003070654,0.0002627358,0.0002783651,0.0003032576,0.00006039999,0.0001044047],"category_scores_gemma":[0.006138172,0.0001828825,0.0001243085,0.0001150227,0.0001203654,0.0004524464,0.0003131629,0.0003328047,0.000004003306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001796417,"about_ca_system_score_gemma":0.0004912918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002110926,"about_ca_topic_score_gemma":0.00007729472,"domain_scores_codex":[0.9964777,0.0004406091,0.001331068,0.0004273007,0.000910369,0.0004129096],"domain_scores_gemma":[0.9949118,0.00274356,0.0006574327,0.0003148588,0.0005502662,0.0008220943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4188565,0.01567501,0.3857664,0.00008848128,0.009451104,0.0001843883,0.03434208,0.0007328091,0.000248757,0.000004388952,0.0006922559,0.1339579],"study_design_scores_gemma":[0.6706075,0.004054136,0.2664735,0.0008772755,0.0006468349,0.00001545578,0.01099768,0.0457978,0.00003749914,0.0001056684,0.00005647452,0.0003301937],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774675,0.000664545,0.004040243,0.005207114,0.0001928396,0.01239882,0.00001264345,0.00001238527,0.000003891952],"genre_scores_gemma":[0.9850336,0.0006085658,0.01123615,0.001119694,0.0001973537,0.001717787,0.00000389443,0.00004997942,0.00003297708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.251751,"threshold_uncertainty_score":0.745773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1737127941850504,"score_gpt":0.369475554435499,"score_spread":0.1957627602504486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}