{"id":"W2089836118","doi":"10.1210/me.2007-0323","title":"Homodimerization of Ror2 Tyrosine Kinase Receptor Induces 14-3-3β Phosphorylation and Promotes Osteoblast Differentiation and Bone Formation","year":2007,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Phosphorylation; Autophosphorylation; Cell biology; Biology; Mesenchymal stem cell; Tyrosine phosphorylation; Receptor tyrosine kinase; Signal transduction; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009558042,0.0001480172,0.0001505591,0.0001374517,0.00007649355,0.00001860903,0.00005449153,0.0001418982,0.0000134632],"category_scores_gemma":[0.0001469818,0.000156372,0.00003499678,0.0001032782,0.0001036973,0.00002327681,0.00008866604,0.00009463067,0.0000025686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001631728,"about_ca_system_score_gemma":0.00001478286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002873997,"about_ca_topic_score_gemma":0.0000375259,"domain_scores_codex":[0.9990388,0.000063892,0.0003030165,0.0002746414,0.0001005021,0.0002191961],"domain_scores_gemma":[0.9994019,0.00001573638,0.0002030855,0.0001850469,0.0001420476,0.00005218976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009765078,0.00005499354,0.0006837666,0.00003553885,0.00002922135,0.000003493215,0.0001005773,0.000007677937,0.9871923,0.0007677529,0.00002647926,0.01100053],"study_design_scores_gemma":[0.0006178733,0.0003664651,0.009775904,0.00002074299,0.00002394606,0.00008205582,0.00008444916,0.00008366222,0.9879183,0.0001894989,0.0006962492,0.0001409049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9632729,0.001195894,0.03470105,0.0002179145,0.0001193707,0.0003338636,0.00001359941,0.00001795783,0.0001274693],"genre_scores_gemma":[0.9974928,0.0002023728,0.001763254,0.00004886192,0.00004304234,0.00002814411,0.000347546,0.0000193653,0.00005459787],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03421993,"threshold_uncertainty_score":0.6376667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006749686747144126,"score_gpt":0.2341713892610583,"score_spread":0.2274217025139141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}