{"id":"W2089849132","doi":"10.1016/j.cardiores.2006.08.012","title":"Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqα/MAP kinase signaling pathways☆","year":2006,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Intracellular; Natriuretic peptide; Endocrinology; Signal transduction; Receptor; Internal medicine; NPR1; Atrial natriuretic peptide; Cell biology; Chemistry; Biology; Pharmacology; Medicine; Heart failure","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001436379,0.0004062279,0.000249397,0.0001033839,0.000138741,0.000161615,0.0001686413,0.0002247789,0.001818919],"category_scores_gemma":[0.0000660982,0.00008843969,0.000245413,0.0000699075,0.0002143438,0.000187061,0.0001575567,0.0006671654,0.0005579402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001236424,"about_ca_system_score_gemma":0.0002186955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003485059,"about_ca_topic_score_gemma":0.0005916458,"domain_scores_codex":[0.9999027,0.00001773649,0.000007384679,0.00001304131,0.00002289501,0.00003623093],"domain_scores_gemma":[0.9999601,0.000005890703,0.000009018145,0.000004025896,0.00000599228,0.0000150185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005682485,0.00009824308,0.00008077548,0.00007974296,0.000007044916,0.0000360186,0.00001183003,0.00003192154,0.9974425,0.00005177456,0.00006046494,0.001531531],"study_design_scores_gemma":[0.0002963623,0.004135283,0.006884206,0.00001963725,0.00004588426,0.0002770323,0.00007513914,0.000823174,0.9836661,0.00008009451,0.003688893,0.000008355118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939702,0.002735882,0.001097284,0.000159855,0.00009586805,0.00004075209,0.0001311261,0.00004407242,0.001725073],"genre_scores_gemma":[0.9917303,0.002641036,0.002104957,0.0001500493,0.00006319572,0.00008603359,0.0003870255,0.00001307638,0.002824209],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001818919,"threshold_uncertainty_score":0.006084919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03506608555925241,"score_gpt":0.2721643923972884,"score_spread":0.237098306838036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}