{"id":"W2089920227","doi":"10.1038/sj.jid.5700413","title":"Pharmacologic Blockade of Angiopoietin-2 Is Efficacious against Model Hemangiomas in Mice","year":2006,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Vascular Malformations and Hemangiomas","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; School of Medicine, Emory University; U.S. Public Health Service; American Skin Association; National Institutes of Health; Dermatology Foundation","keywords":"Angiogenesis; In vivo; Autocrine signalling; Cancer research; Hemangioma; Blockade; Vascular endothelial growth factor; Paracrine signalling; Receptor; Vascular endothelial growth inhibitor; Vascular endothelial growth factor A; Medicine; Biology; Pathology; Internal medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005064611,0.0008918164,0.0006340548,0.001044171,0.0005180436,0.0005885917,0.0006500281,0.0008701443,0.001733695],"category_scores_gemma":[0.0002857647,0.000420562,0.0004971272,0.0003518179,0.0008353716,0.0005971729,0.0001801005,0.002588111,0.0006279934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005088167,"about_ca_system_score_gemma":0.0005544902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007621308,"about_ca_topic_score_gemma":0.001491987,"domain_scores_codex":[0.9995671,0.00007965473,0.00003705596,0.00007817765,0.00009562151,0.0001424016],"domain_scores_gemma":[0.9995567,0.00008208511,0.0001312896,0.00004801865,0.00002467807,0.0001571289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002047604,0.00163569,0.0002112796,0.00007526518,0.00002935413,0.000182717,0.00003841703,0.0003014417,0.9914591,0.0006319535,0.0004861917,0.002900915],"study_design_scores_gemma":[0.0007283757,0.00342069,0.001341083,0.00001532641,0.00005691847,0.0003550748,0.00004284614,0.001730551,0.9895124,0.0001826939,0.002602047,0.0000119745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885374,0.001580419,0.003909696,0.0007981006,0.0002444363,0.0002647737,0.001219929,0.0004329639,0.003012263],"genre_scores_gemma":[0.9859027,0.001775297,0.005204344,0.0003074149,0.0001091151,0.000471725,0.0009330328,0.00008708262,0.005209379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001733695,"threshold_uncertainty_score":0.00579977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01967729322741504,"score_gpt":0.2732087625514858,"score_spread":0.2535314693240708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}