{"id":"W2089980059","doi":"10.1002/mc.10105","title":"Insulin‐like growth factor binding protein‐1 over‐expression in transgenic mice inhibits hepatic preneoplasia","year":2003,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transgene; Biology; Genetically modified mouse; Metallothionein; Immunohistochemistry; Endocrinology; Internal medicine; Insulin-like growth factor-binding protein; Growth factor; Ratón; Insulin-like growth factor; Intraperitoneal injection; Molecular biology; Gene; Immunology; Receptor; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002862708,0.0006087782,0.000783303,0.0007235749,0.0001382708,0.00004583385,0.0002298034,0.0004284566,0.0001077153],"category_scores_gemma":[0.0003120703,0.0005750482,0.0004013452,0.001239853,0.00007840813,0.0002235865,0.00005965405,0.0004534757,0.00006134315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002908732,"about_ca_system_score_gemma":0.0003272437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000151678,"about_ca_topic_score_gemma":0.00002978659,"domain_scores_codex":[0.9962121,0.0003611357,0.0008286568,0.0009091992,0.0008042394,0.0008846294],"domain_scores_gemma":[0.9985239,0.00006181204,0.0001808222,0.0006162087,0.0001632587,0.0004539776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001826431,0.0002730364,0.1285931,0.0003128003,0.00006815747,0.0001724126,0.0004749169,0.000004386673,0.8695433,0.00008386247,0.00004084128,0.0002504821],"study_design_scores_gemma":[0.003247283,0.0003485003,0.08257616,0.000331962,0.0001366976,0.00005098724,0.00008302317,0.00003524541,0.9122717,0.00007456198,0.0003059352,0.0005379576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941797,0.002109677,0.0007559243,0.00009564781,0.0002473657,0.001604518,0.00003617363,0.0001313819,0.0008395832],"genre_scores_gemma":[0.9973649,0.00014896,0.00153215,0.000321768,0.00005112205,0.0001938681,0.00006575693,0.0001431077,0.0001783545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04601696,"threshold_uncertainty_score":0.9996701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0127795815012521,"score_gpt":0.2288380872002737,"score_spread":0.2160585056990216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}