{"id":"W2089987789","doi":"10.1038/ajg.2011.86","title":"Intestinal Serotonin Release, Sensory Neuron Activation, and Abdominal Pain in Irritable Bowel Syndrome","year":2011,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Irritable bowel syndrome; Medicine; Enterochromaffin cell; Gastroenterology; Internal medicine; Serotonin; Tryptase; Abdominal pain; Constipation; Mast cell; Substance P; Diarrhea; Immunology; Receptor; Neuropeptide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002412795,0.000350865,0.000333771,0.0003040629,0.0001346816,0.0001969755,0.0001041804,0.0002833907,0.001021749],"category_scores_gemma":[0.0005767805,0.0001139297,0.0001670931,0.000238333,0.000208769,0.0001837942,0.0001797553,0.0002078456,0.0001043617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001577479,"about_ca_system_score_gemma":0.0000754545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005527828,"about_ca_topic_score_gemma":0.0007963041,"domain_scores_codex":[0.9998882,0.00004113068,0.00001665778,0.00001918107,0.00001963361,0.00001514358],"domain_scores_gemma":[0.9997706,0.0000570941,0.0001007498,0.000006868664,0.000018526,0.00004629807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005070608,0.0002232115,0.9446324,0.000244063,0.0002046917,0.002125845,0.0002152633,0.000175485,0.03481932,0.00003437918,0.0001070574,0.01214754],"study_design_scores_gemma":[0.0000244134,0.000491214,0.9978892,0.000006731182,0.00002921381,0.0009934158,0.00004957252,0.0000797939,0.0003713204,0.000007800083,0.00005571075,0.000001605629],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988016,0.0009397208,0.00005727686,0.0000190636,0.000003272998,0.000005197112,0.00003643139,0.00000209034,0.0001353727],"genre_scores_gemma":[0.999525,0.0002395217,0.00007045565,0.0000160713,0.000007568384,0.000004476095,0.00006965414,4.148459e-7,0.00006684031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001021749,"threshold_uncertainty_score":0.003418088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01743840065594998,"score_gpt":0.2338727842019518,"score_spread":0.2164343835460018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}