{"id":"W2090023887","doi":"10.1097/01.ccm.0000230385.82679.34","title":"Safety and efficacy of affinity-purified, anti–tumor necrosis factor-α, ovine fab for injection (CytoFab) in severe sepsis*","year":2006,"lang":"en","type":"letter","venue":"Critical Care Medicine","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Placebo; Septic shock; Sepsis; Bronchoalveolar lavage; Tumor necrosis factor alpha; Internal medicine; Gastroenterology; Adverse effect; Clinical endpoint; Shock (circulatory); Intensive care; Randomized controlled trial; Surgery; Immunology; Pathology; Intensive care medicine; Lung","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002122024,0.0006662768,0.00209769,0.0005360815,0.0001100501,0.00002037692,0.0001394213,0.0008398368,0.0003381692],"category_scores_gemma":[0.001901155,0.0005147627,0.000305673,0.0003703022,0.0005993377,0.00006817468,0.00007225633,0.001280508,0.000006699751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003896125,"about_ca_system_score_gemma":0.000172653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000850531,"about_ca_topic_score_gemma":0.00008809443,"domain_scores_codex":[0.9964353,0.0001327843,0.001120121,0.0009163587,0.0007181987,0.0006772033],"domain_scores_gemma":[0.9955699,0.002858585,0.0001784332,0.000589977,0.0005777025,0.0002253955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.00143989,0.001386225,0.1112276,0.01684698,0.0004926091,0.002055288,0.001480013,0.000007743355,0.0004638491,0.0004255267,0.8511911,0.01298318],"study_design_scores_gemma":[0.04482233,0.0138461,0.5452844,0.01229227,0.005949527,0.0005967319,0.002107961,0.00005757453,0.002312868,0.0005874273,0.3703566,0.001786289],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2545957,0.01240135,0.000289685,0.7209343,0.001799923,0.004530172,0.001884556,0.0001993822,0.003364947],"genre_scores_gemma":[0.8722204,0.0002021447,0.0003586733,0.1207656,0.002810874,0.0001810855,0.003002784,0.0001413756,0.0003170834],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6176246,"threshold_uncertainty_score":0.9997304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05684513251553614,"score_gpt":0.3492632715324709,"score_spread":0.2924181390169348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}