{"id":"W2090277699","doi":"10.1016/j.bbrc.2008.02.162","title":"Induction of expression and co-localization of heat shock polypeptides with the polyalanine expansion mutant of poly(A)-binding protein N1 after chemical stress","year":2008,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Oculopharyngeal muscular dystrophy; Mutant; Heat shock protein; Poly(A)-binding protein; Protein aggregation; Hsp27; Chemistry; Cell biology; Hsp70; Nucleus; Molecular biology; Messenger RNA; Biology; Biochemistry; Muscular dystrophy; Genetics; Gene; RNA-binding protein","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001988283,0.000530644,0.0003708657,0.0003145009,0.0003304664,0.0004138916,0.0003611987,0.0004461324,0.0009915705],"category_scores_gemma":[0.000251732,0.0002574098,0.0004410542,0.0002669669,0.0004291113,0.0002925726,0.000495565,0.0008450739,0.0005558952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007243335,"about_ca_system_score_gemma":0.0003250758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0015923,"about_ca_topic_score_gemma":0.002243284,"domain_scores_codex":[0.9997509,0.00003867372,0.00002150912,0.00005670494,0.00005059638,0.00008155961],"domain_scores_gemma":[0.9995294,0.0001317085,0.00009634606,0.00007287093,0.00005151228,0.0001182246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001261371,0.00002240474,0.00008181679,0.00001095961,0.000001921247,0.00004063883,0.00001112536,0.00002918055,0.9994431,0.00005010335,0.00001830808,0.0001642415],"study_design_scores_gemma":[0.000008936085,0.00008679097,0.004559492,0.000003271448,0.000005729985,0.0001110205,0.00004188177,0.0006806795,0.9938373,0.00002843454,0.0006305034,0.000006089297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948946,0.0006574637,0.002548798,0.0001516122,0.00006860258,0.00003219803,0.0003447549,0.00006630467,0.001235857],"genre_scores_gemma":[0.9918933,0.0003022434,0.001889694,0.00007251753,0.00001931218,0.00005412408,0.001021716,0.00006893942,0.004678237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0015923,"threshold_uncertainty_score":0.005255401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03084466112133816,"score_gpt":0.3096900099873474,"score_spread":0.2788453488660093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}