{"id":"W2090343027","doi":"10.1016/j.vaccine.2015.01.017","title":"Enhanced protection against Rickettsia rickettsii infection in C3H/HeN mice by immunization with a combination of a recombinant adhesin rAdr2 and a protein fragment rOmpB-4 derived from outer membrane protein B","year":2015,"lang":"en","type":"article","venue":"Vaccine","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Academy of Medical Sciences","keywords":"Rickettsia rickettsii; Biology; Antigen; Antibody; Recombinant DNA; Immunization; Bacterial adhesin; Rocky Mountain spotted fever; Virology; Molecular biology; Microbiology; Immunology; Spotted fever; Rickettsia; Virus; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003056031,0.0003082577,0.0004700482,0.0003096485,0.0001030877,0.00002672702,0.0001052812,0.0002689128,0.0000594696],"category_scores_gemma":[0.0001741131,0.0002726256,0.00004483891,0.0004518556,0.00004154172,0.0003259816,0.00006831641,0.000295264,0.00002998415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002464149,"about_ca_system_score_gemma":0.0001082117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005529532,"about_ca_topic_score_gemma":0.001177336,"domain_scores_codex":[0.9980696,0.0005415833,0.0005284554,0.0004712112,0.00009557002,0.0002935139],"domain_scores_gemma":[0.9989161,0.00003791162,0.0004517232,0.0002752701,0.000268976,0.00004995775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001641831,0.001048823,0.008958599,0.00008538606,0.0001655657,0.000003284053,0.0009113732,0.00004929103,0.9839057,0.00002132519,0.00008947685,0.003119292],"study_design_scores_gemma":[0.0112961,0.001706272,0.07337806,0.0004046599,0.00007264335,0.0000112073,0.0001641275,0.0001944937,0.9119605,0.0002173865,0.0002418986,0.0003526537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916188,0.0007640391,0.003850835,0.0002776773,0.0001774166,0.003102617,0.00001996139,0.0001300725,0.00005859354],"genre_scores_gemma":[0.9982377,0.00005317549,0.0001656243,0.00003446223,0.00001615722,0.0007979682,0.0004319522,0.00004055205,0.0002224326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07194526,"threshold_uncertainty_score":0.9999726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00978095111319353,"score_gpt":0.209193663903575,"score_spread":0.1994127127903815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}