{"id":"W2090343027","doi":"10.1016/j.vaccine.2015.01.017","title":"Enhanced protection against Rickettsia rickettsii infection in C3H/HeN mice by immunization with a combination of a recombinant adhesin rAdr2 and a protein fragment rOmpB-4 derived from outer membrane protein B","year":2015,"lang":"en","type":"article","venue":"Vaccine","topic":"Vector-borne infectious diseases","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Academy of Medical Sciences","keywords":"Rickettsia rickettsii; Biology; Antigen; Antibody; Recombinant DNA; Immunization; Bacterial adhesin; Rocky Mountain spotted fever; Virology; Molecular biology; Microbiology; Immunology; Spotted fever; Rickettsia; Virus; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005683397,0.001875448,0.0008325751,0.0009632789,0.0003241218,0.0005258321,0.0006074025,0.001223648,0.001904214],"category_scores_gemma":[0.0002460758,0.0005443572,0.0006120717,0.0002343062,0.000590283,0.0006017654,0.0003635556,0.002518175,0.0005709485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005361665,"about_ca_system_score_gemma":0.0004690717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008088201,"about_ca_topic_score_gemma":0.0009298854,"domain_scores_codex":[0.9994886,0.00007921035,0.00003315597,0.0001099829,0.00008248002,0.0002066244],"domain_scores_gemma":[0.9996102,0.00006414989,0.0001063266,0.00005722175,0.0000381143,0.0001239305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001769735,0.0007259572,0.0002154112,0.0000767914,0.00002991596,0.00007472371,0.00003242467,0.0002093082,0.9953462,0.0001314994,0.0001154014,0.001272657],"study_design_scores_gemma":[0.0008359884,0.007463465,0.006385243,0.00002930083,0.0001287029,0.0003979662,0.000048676,0.001798614,0.9810289,0.0001440525,0.001716153,0.0000230045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99497,0.0008311616,0.001554957,0.0002055322,0.0001106217,0.000107891,0.0003812265,0.0002669774,0.001571588],"genre_scores_gemma":[0.9928783,0.0005234373,0.001813049,0.0001577789,0.00006945712,0.00009180852,0.0007413636,0.00004798512,0.003676779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001904214,"threshold_uncertainty_score":0.006370246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00978095111319353,"score_gpt":0.209193663903575,"score_spread":0.1994127127903815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}