{"id":"W2090421104","doi":"10.1002/hep.21540","title":"Loss of integrin linked kinase from mouse hepatocytes in vitro and in vivo results in apoptosis and hepatitis†","year":2007,"lang":"en","type":"article","venue":"Hepatology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; McGill University","funders":"National Center for Advancing Translational Sciences; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Integrin-linked kinase; Cell biology; Extracellular matrix; Apoptosis; Integrin; Programmed cell death; Biology; Laminin; Necroptosis; Kinase; Chemistry; Cancer research; Cell; Protein kinase A; Biochemistry; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003019687,0.0006236219,0.0002206638,0.000396768,0.0002028473,0.00035963,0.0002647581,0.0004294935,0.002192866],"category_scores_gemma":[0.0001238841,0.0001992209,0.0002946232,0.0001863513,0.0003109323,0.0002770659,0.0001761919,0.00104537,0.0009411259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000371056,"about_ca_system_score_gemma":0.0001989316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003017368,"about_ca_topic_score_gemma":0.0004920393,"domain_scores_codex":[0.9996701,0.00004732719,0.0000526887,0.00005737239,0.00009343808,0.00007902265],"domain_scores_gemma":[0.9997332,0.000052941,0.00009143032,0.0000321571,0.00002717866,0.00006310639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001507775,0.00003456376,0.0002501197,0.00003695368,0.00000501993,0.00004697916,0.00001053086,0.00002423789,0.9987844,0.00004912994,0.00002300505,0.0005843955],"study_design_scores_gemma":[0.00001632646,0.0002334111,0.001632942,0.000004767484,0.00001282544,0.0002417268,0.00001820003,0.0002757751,0.9966269,0.00001905585,0.0009163157,0.000001868746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840218,0.005319327,0.007097132,0.0003363336,0.00010279,0.00005075803,0.0007049908,0.0002311881,0.002135621],"genre_scores_gemma":[0.9868994,0.001805266,0.003717852,0.0001137501,0.00002049376,0.00009385588,0.001144734,0.00004282818,0.006161879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002192866,"threshold_uncertainty_score":0.007335842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02036036390831144,"score_gpt":0.2971305271399001,"score_spread":0.2767701632315887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}