{"id":"W2090463590","doi":"10.1161/circresaha.107.153346","title":"Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia","year":2007,"lang":"en","type":"article","venue":"Circulation Research","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":289,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Mobilization; Perfusion; Hypoxia (environmental); Ischemia; Medicine; Hypoxia-inducible factors; Angiogenesis; Cardiology; Limb perfusion; Limb ischemia; Internal medicine; Chemistry; Biochemistry; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004491096,0.00007448043,0.00009714273,0.0001255641,0.00005266998,0.000009794655,0.00004195391,0.0001330929,0.00001049952],"category_scores_gemma":[0.00007278749,0.00007203513,0.00004986623,0.0001431674,0.00007873283,0.000008510061,0.00007014228,0.00006231257,6.542282e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001911165,"about_ca_system_score_gemma":0.00003765803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003627104,"about_ca_topic_score_gemma":0.000009125846,"domain_scores_codex":[0.9992148,0.0000716352,0.0001225365,0.0002528972,0.0001823393,0.000155735],"domain_scores_gemma":[0.9994719,0.0001028311,0.00005872011,0.0001644392,0.0001501192,0.00005200981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001549988,0.00005310143,0.04907295,0.000190635,0.000010556,5.601416e-7,0.00005097479,0.00005192072,0.94065,0.000003544207,0.0000266433,0.009734103],"study_design_scores_gemma":[0.0001929037,0.0001627955,0.3180775,0.00003206736,0.000005006731,6.465831e-7,0.00001775671,0.00008598633,0.6812871,0.000010923,0.00007844502,0.000048907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946658,0.003794658,0.001089786,0.000009699454,0.00002815259,0.0002097753,0.000005002219,0.00000248077,0.0001946316],"genre_scores_gemma":[0.9990652,0.0007131896,0.00004986925,0.00001344047,0.00005816686,0.00000902093,0.00001008417,0.00001225397,0.00006882902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2690045,"threshold_uncertainty_score":0.2937507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02432688949921833,"score_gpt":0.3173798825545547,"score_spread":0.2930529930553363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}