{"id":"W2090541084","doi":"10.1002/jcp.21924","title":"p38 MAPK activity is stimulated by vascular endothelial growth factor receptor 2 activation and is essential for shear stress‐induced angiogenesis","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Angiogenesis and VEGF in Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Phosphorylation; Angiogenesis; p38 mitogen-activated protein kinases; Prazosin; Shear stress; Endocrinology; Internal medicine; Stimulation; Vascular endothelial growth factor; MAPK/ERK pathway; Chemistry; Biology; Cell biology; Receptor; Medicine; Materials science; VEGF receptors; Antagonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002379457,0.0006659993,0.0003235173,0.000324529,0.0003111467,0.000260869,0.0001664778,0.000242155,0.001753427],"category_scores_gemma":[0.0002173726,0.0002990231,0.0004281921,0.0001644106,0.0002300038,0.0003301836,0.0002572773,0.0004676221,0.0004741161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003246704,"about_ca_system_score_gemma":0.0003052977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000342845,"about_ca_topic_score_gemma":0.0004133086,"domain_scores_codex":[0.9997827,0.0000326541,0.00001624005,0.00003790413,0.00005449728,0.00007602224],"domain_scores_gemma":[0.9998617,0.00001115202,0.00004979083,0.000009632475,0.00002265646,0.00004499338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002760178,0.0000508822,0.0004442256,0.00008989369,0.000007543817,0.0001552427,0.0000217872,0.00004296151,0.9969495,0.00009231184,0.0001063915,0.001763382],"study_design_scores_gemma":[0.0001548303,0.00120694,0.08729016,0.00003779843,0.00004426343,0.001929469,0.00009228037,0.002995848,0.899121,0.0005119627,0.006592947,0.00002240673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858305,0.00595737,0.005198014,0.0002308604,0.0001047161,0.00006796863,0.0006187909,0.0002216699,0.0017702],"genre_scores_gemma":[0.9911316,0.003060126,0.002965623,0.00003458077,0.00005408344,0.0001214654,0.0006250513,0.00001734205,0.001990103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001753427,"threshold_uncertainty_score":0.005865753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01026958645849739,"score_gpt":0.2506798306283473,"score_spread":0.2404102441698499,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}