{"id":"W2090570866","doi":"10.3390/diseases2010045","title":"MeCP2-Related Diseases and Animal Models","year":2014,"lang":"en","type":"article","venue":"Diseases","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Scottish Rite Charitable Foundation of Canada; Manitoba Health Research Council; Health Sciences Centre Foundation","keywords":"MECP2; Epigenetics; Rett syndrome; DNA methylation; Angelman syndrome; Disease; Biology; Neuroscience; microRNA; Human disease; Bioinformatics; Genetics; Computational biology; Gene; Medicine; Gene expression; Phenotype; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001006499,0.001090486,0.000619366,0.002065613,0.0006166304,0.0007460023,0.001182646,0.001668048,0.005797391],"category_scores_gemma":[0.0006131869,0.0004119017,0.0006188269,0.0008877778,0.0008365178,0.0007525155,0.0008677532,0.001640577,0.001724986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009931183,"about_ca_system_score_gemma":0.0005629988,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001358477,"about_ca_topic_score_gemma":0.001948951,"domain_scores_codex":[0.999366,0.0001895096,0.00008236913,0.0001289989,0.0001763524,0.00005684036],"domain_scores_gemma":[0.9996257,0.0001119305,0.0000895522,0.00008072448,0.00003472324,0.00005752434],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002552098,0.001408693,0.004954576,0.003051985,0.000488653,0.006921831,0.0003219882,0.002256245,0.8177376,0.03807197,0.02229409,0.09994023],"study_design_scores_gemma":[0.0006623417,0.003601971,0.01547802,0.001233297,0.001117122,0.02957921,0.000344642,0.006213331,0.383988,0.02052895,0.5370751,0.0001779429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.4159935,0.3279491,0.1342471,0.01001987,0.002533198,0.002440647,0.02365392,0.003904617,0.0792581],"genre_scores_gemma":[0.5515761,0.2512652,0.1105324,0.004362136,0.0005750486,0.005764144,0.01917696,0.000381632,0.05636635],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.005797391,"threshold_uncertainty_score":0.01939416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00518598100378047,"score_gpt":0.2026093500835394,"score_spread":0.197423369079759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}