{"id":"W2090570866","doi":"10.3390/diseases2010045","title":"MeCP2-Related Diseases and Animal Models","year":2014,"lang":"en","type":"article","venue":"Diseases","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Scottish Rite Charitable Foundation of Canada; Manitoba Health Research Council; Health Sciences Centre Foundation","keywords":"MECP2; Epigenetics; Rett syndrome; DNA methylation; Angelman syndrome; Disease; Biology; Neuroscience; microRNA; Human disease; Bioinformatics; Genetics; Computational biology; Gene; Medicine; Gene expression; Phenotype; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001827013,0.000122552,0.00008854968,0.00002207823,0.0000737193,0.0000249832,0.00008872636,0.0000431732,0.00001870043],"category_scores_gemma":[0.00003528778,0.0001166776,0.00004891031,0.0000382386,0.00007077702,0.000003555087,0.0001047858,0.00002375118,0.00000713736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002177804,"about_ca_system_score_gemma":0.00002307908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003706796,"about_ca_topic_score_gemma":0.000002305437,"domain_scores_codex":[0.9993284,0.00003045699,0.0001033887,0.000291725,0.00008409489,0.0001619431],"domain_scores_gemma":[0.9996209,0.000006934064,0.00002710914,0.0001670026,0.00002175641,0.0001563641],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006897522,0.001048566,0.2605623,0.000206273,0.0003087913,0.00001581376,0.0001716364,0.001871795,0.6804028,0.008961235,0.01988561,0.0258755],"study_design_scores_gemma":[0.001126605,0.0003995681,0.9715378,0.00001515961,0.00009454787,0.000006650355,0.00006581502,0.003513241,0.005769962,0.005591965,0.01138159,0.0004971212],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958513,0.002570192,0.0001358366,0.00008911343,0.00005677353,0.00008716259,0.00006190773,0.00001931621,0.001128431],"genre_scores_gemma":[0.9987643,0.0003965615,0.00006968849,0.0003573529,0.00002162118,0.00001382994,0.0001681007,0.00001928435,0.0001892741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7109755,"threshold_uncertainty_score":0.4757974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00518598100378047,"score_gpt":0.2026093500835394,"score_spread":0.197423369079759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}