{"id":"W2090570929","doi":"10.1016/s0306-4522(00)00329-8","title":"Bi-directional changes in affective state elicited by manipulation of medullary pain-modulatory circuitry","year":2000,"lang":"en","type":"article","venue":"Neuroscience","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; U.S. Public Health Service; Medical Research Council Canada; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Rostral ventromedial medulla; Nociception; Neuroscience; Microinjection; Hyperalgesia; Noxious stimulus; Psychology; Opioid; Chemistry; Medicine; Receptor; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001893224,0.0002820959,0.0003756957,0.0001536271,0.0002068469,0.0003370076,0.0001644865,0.0002473845,0.004504814],"category_scores_gemma":[0.0005473097,0.0001788851,0.000147626,0.000138946,0.0003441905,0.0003212665,0.0003843857,0.0006428224,0.0003396372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001667384,"about_ca_system_score_gemma":0.0002668242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000357739,"about_ca_topic_score_gemma":0.000803237,"domain_scores_codex":[0.9998509,0.00002486666,0.00001024182,0.00003046919,0.00003194767,0.00005158298],"domain_scores_gemma":[0.9998516,0.00004460708,0.00003077702,0.00001674496,0.00001075833,0.00004562095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002578912,0.00006990172,0.0003425074,0.00004605985,0.00001558116,0.00003897067,0.00005081299,0.0001234678,0.9916061,0.0003150656,0.0000539457,0.004758535],"study_design_scores_gemma":[0.0009676459,0.008992342,0.124379,0.00006880042,0.0003332358,0.0008135386,0.0005794439,0.008128677,0.849786,0.002542713,0.003349575,0.00005899535],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931265,0.0004812715,0.003538488,0.0001115057,0.00007401688,0.00005956403,0.0001410201,0.00003650707,0.002431126],"genre_scores_gemma":[0.9964519,0.0003437661,0.001509008,0.00009033452,0.00003115141,0.00008227906,0.00005019177,0.00001793581,0.001423541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004504814,"threshold_uncertainty_score":0.01507008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01577197832760147,"score_gpt":0.2597952860823804,"score_spread":0.244023307754779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}