{"id":"W2090652060","doi":"10.1002/btpr.17","title":"Simpler noninstrumented batch and semicontinuous cultures provide mammalian cell kinetic data comparable to continuous and perfusion cultures","year":2008,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Polytechnique Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Perfusion; Chemistry; Microbiology; Biology; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007919296,0.0002902359,0.0002779536,0.00007905556,0.0003410678,0.00005718688,0.0004266724,0.0004707956,0.00001686777],"category_scores_gemma":[0.0000526439,0.0002392811,0.00003774882,0.0001291055,0.0004680991,0.00001297034,0.001054991,0.0001777411,0.000008167284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008831221,"about_ca_system_score_gemma":0.00003953053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009336977,"about_ca_topic_score_gemma":0.00006184594,"domain_scores_codex":[0.9983011,0.00005488775,0.000247606,0.0008557636,0.0001257658,0.0004148335],"domain_scores_gemma":[0.9988773,0.000006800378,0.0001129858,0.0007478152,0.00007399156,0.0001810364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002198196,0.0002307749,0.0405256,0.00006776954,0.00004547345,0.00004629965,0.0001366798,0.00000646912,0.8787777,0.000046962,0.07078092,0.009115539],"study_design_scores_gemma":[0.001427604,0.001192472,0.006152214,0.00005327627,0.00004902378,0.0004531287,0.0002748604,0.0001242326,0.6483079,0.00003222851,0.3414041,0.0005289969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916141,0.006213923,0.00006958012,0.000911372,0.0001286844,0.0006455353,0.00009932735,0.0001043458,0.0002131283],"genre_scores_gemma":[0.9953763,0.001137724,0.001728559,0.0003693211,0.0001140055,0.00006725075,0.0002442713,0.00002916956,0.0009334048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2706231,"threshold_uncertainty_score":0.9757601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279240147311362,"score_gpt":0.2711856530181737,"score_spread":0.25839325154506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}