{"id":"W2090655441","doi":"10.1016/j.mehy.2006.01.045","title":"Possible acceleration of aging by adjuvant chemotherapy: A cause of early onset frailty?","year":2006,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":148,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; Cape Breton University","funders":"","keywords":"Medicine; Chemotherapy; Breast cancer; Oncology; Cancer; Internal medicine; Adjuvant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002740475,0.0001619298,0.0004800489,0.0001245813,0.00004183287,0.00001077147,0.0001594797,0.0001548099,0.0009159318],"category_scores_gemma":[0.0003603286,0.0001270769,0.0001016946,0.0002674248,0.0002926867,0.00008829121,0.00002522925,0.000189143,0.00001275526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002750647,"about_ca_system_score_gemma":0.0002157283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00142841,"about_ca_topic_score_gemma":0.00007930854,"domain_scores_codex":[0.9980912,0.0000553573,0.0005106488,0.000235538,0.0008396158,0.0002677032],"domain_scores_gemma":[0.9990177,0.000241047,0.0001614436,0.0002957257,0.0001107576,0.0001733547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006294331,0.002357899,0.6699918,0.0007599153,0.0002442542,0.0001994315,0.001833628,0.000002769183,0.1573935,0.0003451679,0.03183826,0.1344039],"study_design_scores_gemma":[0.003287231,0.0007403789,0.536408,0.0009476996,0.0001136186,0.0000917486,0.0002234045,0.000241544,0.4504596,0.0005038384,0.006677186,0.000305711],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953465,0.001502568,0.0004360478,0.001378203,0.00007399865,0.0002020145,0.0000372793,0.00005492409,0.0009684176],"genre_scores_gemma":[0.9972253,0.0002741794,0.0005044424,0.0006029856,0.0001463332,0.000008544167,0.00003168312,0.00002753557,0.001179009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2930661,"threshold_uncertainty_score":0.9999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03042913988135034,"score_gpt":0.2918475321150649,"score_spread":0.2614183922337146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}