{"id":"W2090666183","doi":"10.1006/bbrc.2000.2459","title":"Mutation of the Toxin Binding Site of PP-1c: Comparison with PP-2B","year":2000,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Marine Toxins and Detection Methods","field":"Environmental Science","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Toxin; Chemistry; Amino acid; Mutant; Peptide; Okadaic acid; Docking (animal); Biochemistry; Binding site; Stereochemistry; Enzyme; Phosphatase; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002851665,0.0006311018,0.0008079631,0.0004822046,0.0003944072,0.0004791725,0.0008101194,0.001124187,0.003559423],"category_scores_gemma":[0.0009323619,0.0002819421,0.0007801645,0.0006009326,0.0005346223,0.0002913995,0.0003103873,0.001228074,0.001287882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005543135,"about_ca_system_score_gemma":0.0005311835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004425921,"about_ca_topic_score_gemma":0.001278402,"domain_scores_codex":[0.9994385,0.0001019303,0.00006047822,0.00009917552,0.0001839765,0.0001159756],"domain_scores_gemma":[0.9994374,0.0001776108,0.0001061512,0.00006295261,0.00009288544,0.000122901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000692713,0.0002049257,0.0006178244,0.00009580178,0.00004115965,0.0005149622,0.00005072646,0.001004833,0.9945456,0.0002985294,0.0001537309,0.001779129],"study_design_scores_gemma":[0.00008155953,0.0003774113,0.006354926,0.00002075928,0.00007432803,0.001458057,0.00008286911,0.004879158,0.9841159,0.0001425043,0.002374619,0.0000378408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925452,0.0005393045,0.003785467,0.0001920593,0.0001164037,0.00005085941,0.00101474,0.00007225533,0.001683724],"genre_scores_gemma":[0.9943883,0.000269244,0.002606659,0.0001255488,0.00002166543,0.00003838661,0.001419314,0.00008801149,0.001042819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004425921,"threshold_uncertainty_score":0.0119074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06133433110029799,"score_gpt":0.3727554529590625,"score_spread":0.3114211218587645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}