{"id":"W2090706611","doi":"10.1006/smim.2000.0235","title":"Contemporary models for peripheral tolerance and the classical ‘historical postulate’","year":2000,"lang":"en","type":"article","venue":"Seminars in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council","keywords":"Antigen; Self Tolerance; Selection (genetic algorithm); Biology; Immunology; Neuroscience; Cell biology; T cell; Computer science; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003851796,0.0006179279,0.0006305667,0.001072431,0.001817522,0.003573209,0.001815492,0.002587476,0.007204169],"category_scores_gemma":[0.003631748,0.0002555136,0.000385905,0.0009582188,0.01860218,0.007674749,0.002795207,0.006251518,0.001590378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001950022,"about_ca_system_score_gemma":0.001105275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005238044,"about_ca_topic_score_gemma":0.0004283797,"domain_scores_codex":[0.9990445,0.00038395,0.00003690529,0.0002131317,0.0002072371,0.0001142632],"domain_scores_gemma":[0.9980142,0.001014754,0.0002220166,0.0003383429,0.0002368129,0.0001738626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00003565216,0.0000117475,0.00009083595,0.00006214152,0.000004347374,0.00004508024,0.0003717196,0.0002893601,0.0001374928,0.9873918,0.00325685,0.008303022],"study_design_scores_gemma":[0.000007933631,0.00001728444,0.00008388529,0.00004172033,0.000003610864,0.0001069508,0.0001079696,0.0002399059,0.00008687821,0.9589143,0.04038434,0.000005205475],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.03770895,0.1167943,0.2492172,0.2071361,0.01096768,0.00007765426,0.000257383,0.0003685123,0.3774723],"genre_scores_gemma":[0.8211964,0.04775211,0.02665007,0.03346006,0.01675034,0.0003136505,0.0002669872,0.0001590214,0.05345125],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.007204169,"threshold_uncertainty_score":0.02410036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392435624702307,"score_gpt":0.2232598542637141,"score_spread":0.209335498016691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}