{"id":"W2090753242","doi":"10.1016/j.jalz.2010.05.1305","title":"P2‐255: Ketone bodies, sodium oxybate and Alzheimer's disease: Oxidative stress and neuroprotection","year":2010,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Neuroprotection; Oxidative stress; Pentose phosphate pathway; Antioxidant; Oxidative phosphorylation; Ketone bodies; Chemistry; Biochemistry; Reactive oxygen species; Nicotinamide adenine dinucleotide phosphate; Trypan blue; Pharmacology; Internal medicine; Endocrinology; Biology; Medicine; Metabolism; Glycolysis; Apoptosis; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179799,0.0004069638,0.0002762353,0.0002363703,0.0001927872,0.0003048097,0.0003216254,0.000595606,0.003071194],"category_scores_gemma":[0.00005820606,0.0001063237,0.0001587544,0.0002187689,0.000352684,0.0003429838,0.0002148625,0.0006044567,0.000584126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002630396,"about_ca_system_score_gemma":0.0002824862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000880121,"about_ca_topic_score_gemma":0.001158062,"domain_scores_codex":[0.9999694,0.000007321197,0.000003415782,0.000006561645,0.000006894768,0.000006362822],"domain_scores_gemma":[0.9999672,0.000004414582,0.0000105887,0.000001425501,0.00000532353,0.00001097377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0131258,0.001564839,0.002895116,0.004570229,0.0001780522,0.003071504,0.0001973935,0.000485642,0.6885439,0.004085752,0.006294092,0.2749877],"study_design_scores_gemma":[0.002048726,0.0226836,0.0712937,0.0005854402,0.0005335,0.01238656,0.0004736592,0.00206321,0.7056713,0.007831543,0.1743179,0.0001108853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6126734,0.3614928,0.002987011,0.004191328,0.001193519,0.0001713993,0.0004606519,0.0002156589,0.01661434],"genre_scores_gemma":[0.868055,0.1101406,0.002554302,0.0009874848,0.0006967686,0.0001274261,0.0004588066,0.00001426632,0.0169654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003071194,"threshold_uncertainty_score":0.01027417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377833581297551,"score_gpt":0.263166928621353,"score_spread":0.2493885928083775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}