{"id":"W2090767709","doi":"10.1081/dmr-100000140","title":"MECHANISMS OF 1,1-DICHLOROETHYLENE-INDUCED CYTOTOXICITY IN LUNG AND LIVER<sup>*,†</sup>","year":2001,"lang":"en","type":"review","venue":"Drug Metabolism Reviews","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Cancer Institute","keywords":"Glutathione; Chemistry; Biochemistry; Microsome; Epoxide; Cytotoxicity; Lung; In vivo; Hepatocyte; In vitro; Biology; Internal medicine; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003184313,0.0004328878,0.0003601954,0.000386004,0.000127723,0.0004138255,0.0005216002,0.0006021329,0.001615601],"category_scores_gemma":[0.0001114745,0.0001654279,0.0002410916,0.0001335431,0.0003202562,0.0002558505,0.0002315098,0.0003316373,0.0007902007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005855025,"about_ca_system_score_gemma":0.0001887541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005077873,"about_ca_topic_score_gemma":0.0005358467,"domain_scores_codex":[0.9998568,0.0000472316,0.00001124868,0.00002038417,0.00004000687,0.00002423475],"domain_scores_gemma":[0.9998969,0.00002100059,0.00003602049,0.00001051843,0.00002069978,0.00001489707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000603832,0.0001739215,0.001352136,0.001276591,0.00006102787,0.001136246,0.0000739483,0.001237053,0.9308801,0.004367305,0.001892347,0.05694557],"study_design_scores_gemma":[0.00007607824,0.001894926,0.02043724,0.0001367423,0.00009743351,0.005327609,0.00009815218,0.001868169,0.9195835,0.002025395,0.04841875,0.00003603043],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5379217,0.4127542,0.01818365,0.003236096,0.0003570254,0.0003623964,0.001240495,0.0007538578,0.02519064],"genre_scores_gemma":[0.8734764,0.1075769,0.002678544,0.000693431,0.0001829168,0.0001993248,0.0007010567,0.00002876142,0.01446266],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001615601,"threshold_uncertainty_score":0.00540477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1537125169669722,"score_gpt":0.4410058204818649,"score_spread":0.2872933035148927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}