{"id":"W2090801904","doi":"10.1016/j.cryobiol.2010.04.004","title":"Investigating cryoinjury using simulations and experiments. 1: TF-1 cells during two-step freezing (rapid cooling interrupted with a hold time)","year":2010,"lang":"en","type":"article","venue":"Cryobiology","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Cryoprotectant; Supercooling; Cryopreservation; Intracellular; Cryobiology; Dimethyl sulfoxide; Ice formation; Chemistry; Extracellular; Biophysics; Cell biology; Thermodynamics; Biochemistry; Biology; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027782,0.0003769664,0.0004516149,0.0003111766,0.0007416631,0.0005314539,0.0009286812,0.001172915,0.004182896],"category_scores_gemma":[0.001155615,0.0002564721,0.0004828231,0.0003137166,0.0007075564,0.0006599042,0.0003811234,0.0007017768,0.0002644639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009706643,"about_ca_system_score_gemma":0.0007824144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01157246,"about_ca_topic_score_gemma":0.008119519,"domain_scores_codex":[0.9999295,0.0000103704,0.000002920532,0.00001174101,0.0000154895,0.00002983065],"domain_scores_gemma":[0.9993411,0.0003813624,0.00006898014,0.0000485452,0.00007296038,0.00008707715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002328573,0.0001641482,0.003178003,0.0001295147,0.00003456755,0.0002951708,0.000190016,0.9714812,0.01634029,0.004294598,0.001671639,0.001988071],"study_design_scores_gemma":[0.00006676275,0.000105105,0.001984351,0.00001613401,0.00001735532,0.00003141951,0.0000762998,0.9917435,0.00390151,0.001452025,0.0005850982,0.00002044705],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9767676,0.0003614565,0.009127878,0.0008452407,0.0001172859,0.00005300331,0.001112758,0.0002163894,0.01139843],"genre_scores_gemma":[0.9965205,0.0001312933,0.002086898,0.00006732024,0.00001092196,0.0000507149,0.000292565,0.00004367318,0.0007961458],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01157246,"threshold_uncertainty_score":0.02301019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0317242797419803,"score_gpt":0.3068003053150101,"score_spread":0.2750760255730298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}