{"id":"W2090805771","doi":"10.1002/cncr.23501","title":"Hereditary diffuse gastric cancer","year":2008,"lang":"en","type":"article","venue":"Cancer","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; Creighton University; Nebraska Department of Health and Human Services; U.S. Department of Health and Human Services","keywords":"Medicine; Genetic counseling; CDH1; Cancer; Germline mutation; BRCA mutation; Breast cancer; Genetic testing; Family history; Mutation; Prophylactic Surgery; Oncology; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004420841,0.0001608714,0.0001285464,0.00003301284,0.0001221814,0.000008112415,0.000195339,0.0001127316,0.000681538],"category_scores_gemma":[0.00001190866,0.0001479537,0.00007330882,0.0001312488,0.000101248,0.000004327313,0.00006904575,0.00008743958,0.00002897456],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005150016,"about_ca_system_score_gemma":0.0002934115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001197291,"about_ca_topic_score_gemma":0.00005300852,"domain_scores_codex":[0.9990637,0.00001783096,0.0001500394,0.0003247244,0.000152269,0.0002913792],"domain_scores_gemma":[0.9995474,0.00000458804,0.00005516739,0.0002122953,0.0000854215,0.00009516699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001765534,0.0001027038,0.118011,0.00003475764,0.0002321068,0.0000516041,0.0002329281,0.0003934382,0.346755,0.00001312019,0.5218569,0.01213991],"study_design_scores_gemma":[0.001908357,0.0001227563,0.05295736,0.00006271518,0.00004866368,0.0000772123,0.00004763645,0.00003891665,0.3176252,0.00004228717,0.6263676,0.0007013091],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805786,0.01617624,0.0002083504,0.0002792549,0.0009801964,0.000109039,0.00003437412,0.00002875172,0.001605168],"genre_scores_gemma":[0.9756798,0.007946285,0.0002930607,0.001102216,0.001675691,0.0002426483,0.00005811643,0.00003730265,0.01296491],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1045107,"threshold_uncertainty_score":0.7462363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885842159344342,"score_gpt":0.2540706609120632,"score_spread":0.2352122393186197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}