{"id":"W2090805771","doi":"10.1002/cncr.23501","title":"Hereditary diffuse gastric cancer","year":2008,"lang":"en","type":"article","venue":"Cancer","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; BC Cancer Agency","funders":"National Cancer Institute; National Institutes of Health; Creighton University; Nebraska Department of Health and Human Services; U.S. Department of Health and Human Services","keywords":"Medicine; Genetic counseling; CDH1; Cancer; Germline mutation; BRCA mutation; Breast cancer; Genetic testing; Family history; Mutation; Prophylactic Surgery; Oncology; Internal medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001179371,0.000551549,0.0002607852,0.0005469181,0.0004141128,0.00021918,0.0001707422,0.0002188881,0.00708948],"category_scores_gemma":[0.0005157951,0.00009866869,0.0001429036,0.0006576756,0.0003429234,0.0001169093,0.0003515437,0.0002041804,0.0005566454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003538845,"about_ca_system_score_gemma":0.0002860811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003036793,"about_ca_topic_score_gemma":0.003602116,"domain_scores_codex":[0.9998839,0.00001155211,0.000005687576,0.00003186155,0.00002761403,0.00003935378],"domain_scores_gemma":[0.999841,0.00002792262,0.00004336329,0.00001680272,0.00002317341,0.00004773165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004818481,0.00008986306,0.7499182,0.0004276608,0.0001851362,0.1372255,0.0008052373,0.0004566566,0.01894087,0.002500959,0.007133362,0.08183483],"study_design_scores_gemma":[0.00005482153,0.0002587822,0.4277699,0.0001091044,0.0001789887,0.5396677,0.000338531,0.000405247,0.003080413,0.0007580903,0.027363,0.00001541392],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793127,0.004336118,0.0009286847,0.0002259597,0.00003560886,0.0000403009,0.000720181,0.00009519961,0.01430521],"genre_scores_gemma":[0.9953476,0.001154377,0.0004173678,0.00009419114,0.00002754107,0.000009810403,0.0004547377,0.000008012708,0.002486446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00708948,"threshold_uncertainty_score":0.02371663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885842159344342,"score_gpt":0.2540706609120632,"score_spread":0.2352122393186197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}