{"id":"W2090830396","doi":"10.1038/ng.464","title":"Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy","year":2009,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":256,"is_retracted":false,"has_abstract":false,"ca_institutions":"Credit Valley Hospital","funders":"","keywords":"Biology; Dorsal root ganglion; Neuroscience; Sensory system; Golgi apparatus; Gene knockdown; Cell biology; Genetics; Apoptosis; Endoplasmic reticulum","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009303288,0.000150943,0.0001160433,0.00007240272,0.00006034866,0.00003446882,0.00009723074,0.0003459518,0.000005238876],"category_scores_gemma":[0.00002620905,0.0001642479,0.00004910392,0.00009442597,0.00003551626,0.000004619847,0.0000212964,0.0002885306,0.00000298484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001469913,"about_ca_system_score_gemma":0.00005591607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005700021,"about_ca_topic_score_gemma":0.00009587774,"domain_scores_codex":[0.9991181,0.00003797232,0.0001993845,0.0003469365,0.00009774849,0.0001998176],"domain_scores_gemma":[0.9995974,0.000004213923,0.00005431361,0.0002268265,0.00004760148,0.00006960608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003835681,0.0000313523,0.003875706,0.00001173474,0.000009727556,0.00003405887,0.0001545808,0.000328655,0.9938189,0.00004848636,0.00004025997,0.001608178],"study_design_scores_gemma":[0.003499582,0.0007500716,0.3529176,0.00009867921,0.0001415042,0.0002146639,0.0003135058,0.002667315,0.5834436,0.001366071,0.05332943,0.001257943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956275,0.002461338,0.0008099213,0.0003137605,0.0001189198,0.0002941063,0.00001698402,0.00001611709,0.0003413669],"genre_scores_gemma":[0.9973131,0.0003049878,0.0008325105,0.0004699349,0.000137154,0.000006459609,0.000522115,0.00001704343,0.0003967416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4103752,"threshold_uncertainty_score":0.6697837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008315726229226907,"score_gpt":0.2343153630369029,"score_spread":0.225999636807676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}