{"id":"W2090957277","doi":"10.1111/j.1365-2516.2007.01567.x","title":"Staunch protections: the ethics of haemophilia gene transfer research","year":2007,"lang":"en","type":"review","venue":"Haemophilia","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"University of Pennsylvania","keywords":"Haemophilia; Medicine; Clinical trial; Disadvantaged; Gene transfer; Law; Pediatrics; Political science; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003134716,0.0004227456,0.0007877669,0.0002388259,0.0002572667,0.00003043637,0.0007606835,0.001106493,0.0000354797],"category_scores_gemma":[0.0004305373,0.0003021591,0.0005521977,0.0006438009,0.0003850836,0.000002222306,0.0002102701,0.00178709,0.00002883694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004457247,"about_ca_system_score_gemma":0.0005392584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004120022,"about_ca_topic_score_gemma":0.00005720259,"domain_scores_codex":[0.9969451,0.0004777155,0.0007241948,0.000634316,0.0006373761,0.0005812653],"domain_scores_gemma":[0.9979562,0.0002107131,0.00007987882,0.001246605,0.0003904943,0.0001160661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004570201,0.0001435469,0.000001972033,0.0160151,0.0005435733,0.00002466422,0.0003578625,0.00009679648,0.005703044,0.0004459249,0.002882852,0.973739],"study_design_scores_gemma":[0.000128881,0.0001947969,0.000004311809,0.001353537,0.0001664173,0.00009890269,0.00003876461,0.000004236894,0.01104816,0.0001056343,0.9865465,0.0003098493],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001072188,0.99019,0.00682415,0.0001207052,0.0003680286,0.001600802,0.0001090872,0.0000190948,0.0006609646],"genre_scores_gemma":[0.0007093712,0.9962808,0.0003760773,0.00003324749,0.0008061322,0.0002357341,0.0001662227,0.0001063392,0.001286051],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9836637,"threshold_uncertainty_score":0.9999431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2061255089900724,"score_gpt":0.4972051936361133,"score_spread":0.2910796846460409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}