{"id":"W2090961526","doi":"10.1097/tp.0b013e318169be24","title":"Intensified Postgrafting Immunosuppression Failed to Assure Long-Term Engraftment of Dog Leukocyte Antigen-Identical Canine Marrow Grafts After 1 Gray Total Body Irradiation","year":2008,"lang":"en","type":"article","venue":"Transplantation","topic":"Xenotransplantation and immune response","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute","keywords":"Total body irradiation; Immunosuppression; Medicine; Bone marrow; Antigen; Immune system; CD8; Pathology; Immunology; Surgery; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002783599,0.000317142,0.0004980642,0.0003971077,0.0001439109,0.00002333112,0.00009774959,0.000181147,0.0002672849],"category_scores_gemma":[0.00005591476,0.0002860669,0.0002031976,0.0003516877,0.00008366173,0.0002594467,0.00001101552,0.0002569254,0.00007502409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001037858,"about_ca_system_score_gemma":0.0001414918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001942973,"about_ca_topic_score_gemma":0.00004582275,"domain_scores_codex":[0.99757,0.0001848679,0.0008280406,0.0004056379,0.000625305,0.0003861717],"domain_scores_gemma":[0.9988947,0.0001227265,0.0001738015,0.0003059577,0.0002818962,0.0002208977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01132458,0.0003207694,0.1513163,0.0004731081,0.0001807596,0.0007921623,0.005872778,0.00007413823,0.8290651,0.00001804986,0.00006602722,0.0004961882],"study_design_scores_gemma":[0.003566381,0.0004622146,0.7482665,0.0005142024,0.0002521071,0.0005803928,0.00006223097,0.0001830032,0.2458792,0.000001663902,0.00001618541,0.00021588],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936686,0.000314254,0.004012624,0.0004830423,0.0002854571,0.0009470155,0.00009544682,0.0001047349,0.00008879623],"genre_scores_gemma":[0.9965651,0.0008401032,0.0008346547,0.0002691498,0.00007320636,0.00006708517,0.001002082,0.0000475431,0.0003010829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5969502,"threshold_uncertainty_score":0.9999592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01313463682596202,"score_gpt":0.2736692683824979,"score_spread":0.2605346315565359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}