{"id":"W2090966153","doi":"10.1021/nl034267i","title":"Duplex Pinching:  A Structural Switch Suitable for Contractile DNA Nanoconstructions","year":2003,"lang":"en","type":"article","venue":"Nano Letters","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Guanine; Duplex (building); DNA; Chemistry; Intramolecular force; Biophysics; A-DNA; Conformational change; Crystallography; Stereochemistry; Biochemistry; Biology; Nucleotide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205955,0.0002399297,0.0001521614,0.0001166379,0.0001887039,0.0003398607,0.000278902,0.0003625709,0.001844786],"category_scores_gemma":[0.000294882,0.0001928179,0.00008858605,0.00007399773,0.0003371453,0.0003462807,0.0002666052,0.0004079803,0.000352043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001661511,"about_ca_system_score_gemma":0.00009395675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009753583,"about_ca_topic_score_gemma":0.0001581628,"domain_scores_codex":[0.9998906,0.00001223423,0.000007442827,0.0000382703,0.00002892747,0.00002251886],"domain_scores_gemma":[0.9998595,0.0000379401,0.00002843263,0.00001785146,0.00001031034,0.00004588822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002949638,0.00000582939,0.00002400533,0.000014961,0.00000109113,0.00003882876,0.00001612544,0.00006211183,0.9982743,0.0002925744,0.00003910946,0.001201489],"study_design_scores_gemma":[0.00001223389,0.000109167,0.0003884513,0.000002229496,0.000003199471,0.0001927329,0.00001079255,0.001270622,0.9949581,0.0001118802,0.002933655,0.000006976813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9740173,0.0009202279,0.02013004,0.0002086623,0.0001819499,0.00006213043,0.00008844724,0.0004522881,0.003938952],"genre_scores_gemma":[0.992207,0.0002343851,0.004832799,0.00009917527,0.00002003952,0.0000387854,0.00005315136,0.00003438458,0.002480392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001844786,"threshold_uncertainty_score":0.006171465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007912881751031426,"score_gpt":0.2607281199870315,"score_spread":0.2528152382360001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}