{"id":"W2090983971","doi":"10.1021/ma102354k","title":"Facile Construction of Multifunctional Nanocarriers Using Sequential Click Chemistry for Applications in Biology","year":2011,"lang":"en","type":"article","venue":"Macromolecules","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Nanocarriers; Click chemistry; Dendrimer; Chemistry; Ethylene glycol; Combinatorial chemistry; Glutathione; Covalent bond; Conjugated system; Alkyne; PEG ratio; Azide; Polymer chemistry; Organic chemistry; Drug delivery; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003112855,0.0004287,0.0002488329,0.0002254759,0.0001466455,0.0003040757,0.0002452378,0.0003813283,0.0009685792],"category_scores_gemma":[0.0001956128,0.0002895509,0.0002249403,0.0001600936,0.0002098043,0.0003825088,0.0003032922,0.00037622,0.0004395761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004414202,"about_ca_system_score_gemma":0.0002837811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003174979,"about_ca_topic_score_gemma":0.0005172904,"domain_scores_codex":[0.9998618,0.00001429937,0.00001712889,0.00003593613,0.00004160756,0.00002916973],"domain_scores_gemma":[0.9998955,0.00001903577,0.00003798433,0.00001387213,0.00001275226,0.00002083292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002892778,0.00001108819,0.00002946793,0.0000209201,0.000002501494,0.00002333151,0.000008116629,0.000089056,0.9977673,0.0002754285,0.00004026449,0.001703522],"study_design_scores_gemma":[0.000007431305,0.0000564745,0.0001675464,0.000001138353,0.000004841484,0.00007374182,0.000001914741,0.0005217143,0.997666,0.00003209486,0.001463042,0.000004101539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8991363,0.003180895,0.09131851,0.0003970907,0.0000925661,0.0003093758,0.0004930429,0.0009576605,0.00411451],"genre_scores_gemma":[0.9359625,0.001492219,0.05745528,0.0001435663,0.00002232091,0.0001606738,0.0004172897,0.00006018112,0.004285896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009685792,"threshold_uncertainty_score":0.003240228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03890409375380111,"score_gpt":0.2918305812161052,"score_spread":0.2529264874623041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}