{"id":"W2091031746","doi":"10.1158/0008-5472.sabcs12-p2-10-02","title":"Abstract P2-10-02: Clinical validation of the PAM50 risk of recurrence (ROR) score for predicting residual risk of distant-recurrence (DR) after endocrine therapy in postmenopausal women with ER+ early breast cancer (EBC): An ABCSG study","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Vancouver Coastal Health","funders":"","keywords":"Medicine; Anastrozole; Internal medicine; Breast cancer; Oncology; Tamoxifen; Population; Aromatase inhibitor; Hormonal therapy; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003964385,0.0003130246,0.0007806856,0.0002511062,0.0001360879,0.00002142212,0.0005134263,0.0001083986,0.0003090972],"category_scores_gemma":[0.0004493096,0.0002059061,0.00008672666,0.0009093682,0.0009136604,0.000555063,0.0001397031,0.001056982,9.976994e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004789844,"about_ca_system_score_gemma":0.00104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005410478,"about_ca_topic_score_gemma":0.001403778,"domain_scores_codex":[0.9950549,0.0008666122,0.001085046,0.0006264758,0.001407051,0.0009599187],"domain_scores_gemma":[0.995702,0.0008636891,0.0008373804,0.0009504444,0.001362679,0.0002838454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03054756,0.001482429,0.8880678,0.0002613504,0.0003450688,0.000003588567,0.007196799,0.0000791365,0.004425769,0.000005796821,0.00001584866,0.06756884],"study_design_scores_gemma":[0.005961653,0.004655781,0.9733803,0.001054506,0.00009826927,0.000006361188,0.003309131,0.00001325297,0.011151,0.0001001672,0.00007997004,0.0001896251],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920509,0.00256015,0.00002859055,0.0001603155,0.0002435823,0.003005633,0.001914183,0.00001855126,0.00001813008],"genre_scores_gemma":[0.9961125,0.001412727,0.0001523622,0.00001231033,0.0004713041,0.001714311,0.00001399393,0.00006709838,0.00004344144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08531247,"threshold_uncertainty_score":0.8396606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09064113353943677,"score_gpt":0.4442819292444879,"score_spread":0.3536407957050512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}