{"id":"W2091031746","doi":"10.1158/0008-5472.sabcs12-p2-10-02","title":"Abstract P2-10-02: Clinical validation of the PAM50 risk of recurrence (ROR) score for predicting residual risk of distant-recurrence (DR) after endocrine therapy in postmenopausal women with ER+ early breast cancer (EBC): An ABCSG study","year":2012,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; Vancouver Coastal Health","funders":"","keywords":"Medicine; Anastrozole; Internal medicine; Breast cancer; Oncology; Tamoxifen; Population; Aromatase inhibitor; Hormonal therapy; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003323096,0.0005248687,0.000516974,0.0004104727,0.0002727463,0.000516939,0.0005884413,0.0006381171,0.002556689],"category_scores_gemma":[0.003960581,0.0002944643,0.0003230765,0.0002801549,0.0003758438,0.0003607759,0.0004692793,0.0004609922,0.001293718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001989499,"about_ca_system_score_gemma":0.0002674265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007692365,"about_ca_topic_score_gemma":0.0007699897,"domain_scores_codex":[0.9991863,0.0004720589,0.00005901797,0.000129155,0.0001164125,0.00003707246],"domain_scores_gemma":[0.9981406,0.0005640993,0.0003275887,0.0003227317,0.00031253,0.0003323995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04169534,0.001152785,0.9344265,0.00009780579,0.000277848,0.0001326972,0.000125339,0.0003942008,0.004950172,0.00005146297,0.0007329655,0.01596292],"study_design_scores_gemma":[0.005368402,0.01785083,0.9712516,0.00002096144,0.0003265768,0.0007097223,0.00008888131,0.002056639,0.00135396,0.00007335398,0.0008789622,0.00002002078],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987232,0.0001067583,0.0001271208,0.00003103962,0.000006382315,0.0001481181,0.0003693248,0.000008128171,0.0004797429],"genre_scores_gemma":[0.9977114,0.00003830639,0.0004284306,0.00004805889,0.0000207444,0.000160666,0.001261157,0.000004807941,0.0003265054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003323096,"threshold_uncertainty_score":0.01757443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09064113353943677,"score_gpt":0.4442819292444879,"score_spread":0.3536407957050512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}