{"id":"W2091074069","doi":"10.1371/journal.pone.0026430","title":"Dynein Light Chain Tctex-Type 1 Modulates Orexin Signaling through Its Interaction with Orexin 1 Receptor","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; McGill University","keywords":"Orexin; Internalization; Orexin-A; Cell biology; Biology; Orexin receptor; Dynein; Endosome; Intracellular; G protein-coupled receptor; Receptor; Signal transduction; Biochemistry; Neuropeptide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008342831,0.0001610738,0.0001766877,0.00009153178,0.0001369991,0.0002305399,0.0001089892,0.0001880888,0.001073896],"category_scores_gemma":[0.0001141612,0.00009934438,0.0002099467,0.00007103816,0.0001187554,0.0001649405,0.000156127,0.0003112309,0.0002730089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004442158,"about_ca_system_score_gemma":0.0001506408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006263938,"about_ca_topic_score_gemma":0.0010033,"domain_scores_codex":[0.9998958,0.00001832908,0.000007237695,0.00002006049,0.00001716837,0.00004138983],"domain_scores_gemma":[0.9999151,0.00001212181,0.00003008652,0.000004246836,0.000007874742,0.00003059957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001540536,0.00001585798,0.0003510556,0.00002633868,0.000003981328,0.00005842868,0.000009299282,0.00003818411,0.9989781,0.00003034318,0.00002613571,0.00030823],"study_design_scores_gemma":[0.00005569024,0.000416258,0.06974307,0.0000201282,0.00003537066,0.0005211365,0.0000957471,0.002674445,0.9236274,0.00006837668,0.002729538,0.00001285587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983524,0.0007185531,0.0002560424,0.00005666921,0.000009081189,0.000005154895,0.00009010978,0.000009540612,0.0005024549],"genre_scores_gemma":[0.9977205,0.0005092566,0.0002851825,0.00005826871,0.000004438126,0.00001088233,0.0001827188,0.000005195965,0.001223507],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001073896,"threshold_uncertainty_score":0.003592551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2025027081214351,"score_gpt":0.285338942893042,"score_spread":0.0828362347716069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}