{"id":"W2091141535","doi":"10.2353/ajpath.2007.060351","title":"Overexpression of Notch1 Ectodomain in Myeloid Cells Induces Vascular Malformations through a Paracrine Pathway","year":2007,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Kruppel-like factors research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Cancer Institute","keywords":"Paracrine signalling; Ectodomain; Myeloid cells; Myeloid; Biology; Cancer research; Cell biology; Immunology; Pathology; Medicine; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009694057,0.0001419864,0.0003772975,0.0002124594,0.00003191057,0.000006290425,0.0003122732,0.0001129191,0.00002858443],"category_scores_gemma":[0.0001641209,0.0001196578,0.0001555684,0.0002921493,0.000348751,0.00001762298,0.0001252509,0.000305951,0.000004690954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003406672,"about_ca_system_score_gemma":0.0001554193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006123618,"about_ca_topic_score_gemma":0.0000271291,"domain_scores_codex":[0.998272,0.0002691187,0.0006541595,0.0001757315,0.0002682372,0.0003607663],"domain_scores_gemma":[0.9987844,0.00007739772,0.0005689823,0.0002810085,0.0001931906,0.00009504901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001983075,0.0001486202,0.005369662,0.00001160957,0.00003070721,0.0001172058,0.0004085025,0.00009825024,0.9852132,0.00002900731,0.00008472315,0.008290227],"study_design_scores_gemma":[0.0008476401,0.001704796,0.0265696,0.00004901604,0.000009232866,0.0003490681,0.00132745,0.000004890055,0.9659884,0.0001380225,0.002867209,0.0001446656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930714,0.0002758064,0.005940903,0.00007676904,0.00008860911,0.00009660285,0.00001626451,0.00000226195,0.0004313878],"genre_scores_gemma":[0.993515,0.0002927631,0.005899697,0.0001288957,0.0001127214,0.00000216703,0.00001182447,0.00001721844,0.00001977197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02119993,"threshold_uncertainty_score":0.4879503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01121289903132321,"score_gpt":0.2945004243075775,"score_spread":0.2832875252762543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}