{"id":"W2091218337","doi":"10.1210/jc.2012-1598","title":"Distinguishing Constitutional Delay of Growth and Puberty from Isolated Hypogonadotropic Hypogonadism: Critical Appraisal of Available Diagnostic Tests","year":2012,"lang":"en","type":"review","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children","keywords":"Hypogonadotropic hypogonadism; Medicine; Delayed puberty; Basal (medicine); Gonadotropin; Internal medicine; Endocrinology; Etiology; Human chorionic gonadotropin; Pediatrics; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.002474424,0.0006035912,0.006883796,0.0003337533,0.0001012967,0.00001459992,0.0006805318,0.0005547552,0.0002014317],"category_scores_gemma":[0.1071481,0.0003593894,0.001183283,0.0002624859,0.005019202,0.0002245084,0.000330117,0.002797956,0.00002693305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000311595,"about_ca_system_score_gemma":0.00138895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001347356,"about_ca_topic_score_gemma":0.000004355042,"domain_scores_codex":[0.9912829,0.002020778,0.004815047,0.0004955638,0.000697042,0.0006887065],"domain_scores_gemma":[0.9315283,0.06235601,0.003622269,0.0008056656,0.001203867,0.0004839465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002348244,0.003439967,0.02194896,0.008389628,0.01314405,0.001153333,0.0003206091,0.000002330892,0.0003619137,0.03688785,0.00174526,0.9102579],"study_design_scores_gemma":[0.006001494,0.001037464,0.05707617,0.006451534,0.05229114,0.0158169,0.000052644,0.00001451596,0.00003750316,0.002103596,0.8584601,0.000656887],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01728896,0.9772909,0.0004272949,0.001049334,0.002929845,0.0005056572,0.0001357599,0.00001772705,0.000354476],"genre_scores_gemma":[0.1278563,0.8668879,0.002240775,0.00008672284,0.002817533,0.000009888039,0.00001991385,0.00004823409,0.00003265667],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.909601,"threshold_uncertainty_score":0.9998858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1161007296562138,"score_gpt":0.4061445752746033,"score_spread":0.2900438456183895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}