{"id":"W2091223699","doi":"10.1016/j.tetasy.2009.02.015","title":"2-Acetamino-1,2-dideoxynojirimycin—lysine hybrids as hexosaminidase inhibitors","year":2009,"lang":"en","type":"article","venue":"Tetrahedron Asymmetry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; University of British Columbia","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Lysine; Moiety; Epimer; Chemistry; Reductive amination; Stereochemistry; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871585,0.0003046356,0.000282878,0.0001884325,0.0001465348,0.0004045966,0.0002924097,0.0002889327,0.0005809839],"category_scores_gemma":[0.00009475744,0.0001766233,0.0001209918,0.0001956154,0.0001502973,0.0002751978,0.0001691851,0.000399175,0.0002748508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007490223,"about_ca_system_score_gemma":0.0001563692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000714626,"about_ca_topic_score_gemma":0.001472866,"domain_scores_codex":[0.9998924,0.00001933504,0.000008027325,0.0000220745,0.00002179204,0.00003641317],"domain_scores_gemma":[0.9999471,0.00001045366,0.00001336461,0.000007188523,0.000008094337,0.00001383443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002468169,0.00002405433,0.00009123956,0.00003771263,0.000009548179,0.0000718346,0.00001716029,0.0004167167,0.9953144,0.0004539106,0.00009530689,0.003221429],"study_design_scores_gemma":[0.00002685581,0.0001598829,0.0004313241,0.000002344192,0.00001019269,0.00007344242,0.000008240665,0.0006618186,0.9947685,0.00002995045,0.003822647,0.000004935525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789419,0.007013774,0.006015071,0.0001602447,0.0001458328,0.00005743147,0.0002870662,0.000189238,0.007189472],"genre_scores_gemma":[0.9934289,0.001445698,0.001920929,0.00004397065,0.000009860376,0.00002400198,0.0001557173,0.00002001841,0.002950907],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007490223,"threshold_uncertainty_score":0.005434573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007620935175540949,"score_gpt":0.2351857143177934,"score_spread":0.2275647791422525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}