{"id":"W2091286425","doi":"10.1074/jbc.m114.630368","title":"Transforming Growth Factor-β and Interleukin-1β Signaling Pathways Converge on the Chemokine CCL20 Promoter","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Neurological Disorders and Stroke; Fonds Léon Fredericq; European Commission; York University; Tobacco-Related Disease Research Program","keywords":"CCL20; C-C chemokine receptor type 6; Chemokine; Cell biology; Biology; Chemokine receptor; Chemistry; Immunology; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006083437,0.000240103,0.0002847967,0.00001936696,0.00006479095,0.00004058034,0.0003450509,0.0002941405,0.00005967099],"category_scores_gemma":[0.0005268923,0.0001364999,0.0001736353,0.00006325958,0.0001770781,0.00000766043,0.00008701426,0.0004067587,0.000002986686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003654985,"about_ca_system_score_gemma":0.00009361824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001270471,"about_ca_topic_score_gemma":1.751008e-7,"domain_scores_codex":[0.9987266,0.00006828106,0.0004435997,0.0002624852,0.0002299596,0.0002690592],"domain_scores_gemma":[0.9990131,0.0000712732,0.0002775449,0.0001805538,0.0002303881,0.0002271779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003163858,0.00007762222,0.001083174,0.00002329951,0.00006127534,0.00003200718,0.000125397,0.000003630229,0.9976413,0.00003120186,0.0002648599,0.0003398218],"study_design_scores_gemma":[0.0007670581,0.000876421,0.0001185389,0.00006525528,0.00001567653,0.000264617,0.0002179277,0.000008931436,0.994563,0.000444498,0.002466243,0.0001918526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997797,0.0004666642,0.000372592,0.0004952723,0.0001025301,0.00009835042,0.00001878589,0.0000105964,0.0006382659],"genre_scores_gemma":[0.9986645,0.00007996857,0.0001799179,0.0004240136,0.0005600594,0.000004283491,0.00001424878,0.00001723471,0.00005580139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003078346,"threshold_uncertainty_score":0.5566305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04816771372680204,"score_gpt":0.2430834970780564,"score_spread":0.1949157833512544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}