{"id":"W2091330377","doi":"10.1097/00003246-200103000-00006","title":"Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients","year":2001,"lang":"en","type":"article","venue":"Critical Care Medicine","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":291,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Septic shock; Sepsis; Placebo; Tumor necrosis factor alpha; Shock (circulatory); Randomized controlled trial; Multicenter trial; Double blind; Internal medicine; Multicenter study; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001938047,0.001357244,0.002500328,0.0003528836,0.000420062,0.0006536623,0.0005677565,0.001229559,0.003245448],"category_scores_gemma":[0.001073692,0.0005483995,0.0008118621,0.0004406863,0.0007240004,0.0005825851,0.0002928455,0.001703279,0.0005090056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004360385,"about_ca_system_score_gemma":0.001007239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003957951,"about_ca_topic_score_gemma":0.0009301561,"domain_scores_codex":[0.9994873,0.0002866714,0.00003495918,0.00007350425,0.00004587608,0.00007172398],"domain_scores_gemma":[0.9994195,0.0001231755,0.0001508301,0.00002793271,0.00003717217,0.0002414171],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9569951,0.01432105,0.002412883,0.0004888372,0.0004776977,0.0000665238,0.00004714168,0.0002984884,0.007227901,0.0000604069,0.0007770063,0.0168269],"study_design_scores_gemma":[0.9366475,0.05978186,0.002551342,0.00001407894,0.000138521,0.0000386005,0.00001015668,0.0001662753,0.0003400416,0.0000291381,0.0002765,0.000006052656],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889668,0.003659863,0.0005740293,0.0004468554,0.0002214193,0.004604478,0.0005348539,0.00006741176,0.0009242878],"genre_scores_gemma":[0.98707,0.002481767,0.001685667,0.0008459397,0.000413767,0.005341051,0.0006963174,0.00001062403,0.001454978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003245448,"threshold_uncertainty_score":0.01085711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04635792929677697,"score_gpt":0.3461992551563845,"score_spread":0.2998413258596075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}