{"id":"W2091345530","doi":"10.1161/01.hyp.0000126920.93207.53","title":"Characterization of a cGMP-Response Element in the Guanylyl Cyclase/Natriuretic Peptide Receptor A Gene Promoter","year":2004,"lang":"en","type":"article","venue":"Hypertension","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Medical Research Council; Canadian Institutes of Health Research","keywords":"Luciferase; Promoter; NPR1; Transcription (linguistics); Molecular biology; Reporter gene; Response element; NPR2; Biology; Gene; Transcription factor; Atrial natriuretic peptide; Receptor; Transfection; Chemistry; Natriuretic peptide; Gene expression; Biochemistry; Internal medicine; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004298802,0.0003634485,0.0003997285,0.0004059887,0.0002291383,0.0003456318,0.0004397561,0.0003968738,0.001458348],"category_scores_gemma":[0.0006186518,0.0003245355,0.0008123353,0.0002438419,0.0003471942,0.0002312097,0.0002641547,0.0009941232,0.001141762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004190167,"about_ca_system_score_gemma":0.0007286994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001300273,"about_ca_topic_score_gemma":0.001265503,"domain_scores_codex":[0.9997012,0.000053297,0.0000289009,0.0001004924,0.00006689552,0.00004916167],"domain_scores_gemma":[0.9993369,0.0002720726,0.00009684943,0.00005035505,0.0001063917,0.000137407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007503377,0.00004098452,0.0002087677,0.00003670099,0.000002772267,0.00005403882,0.00001998624,0.00008887694,0.9983865,0.0001155076,0.00001155861,0.0009593667],"study_design_scores_gemma":[0.00006542036,0.00042942,0.00782464,0.0000541308,0.00003030405,0.0006795481,0.00005125608,0.004143189,0.9815164,0.0002597444,0.004928986,0.00001702184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.94493,0.002142652,0.04823812,0.0002182903,0.00007484047,0.0002640724,0.001564543,0.0001422937,0.002425242],"genre_scores_gemma":[0.9010912,0.00123556,0.08191772,0.0003207577,0.00005652495,0.0002242202,0.01025442,0.0001290734,0.004770626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001458348,"threshold_uncertainty_score":0.00487864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02009175547004902,"score_gpt":0.2422959642055028,"score_spread":0.2222042087354538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}