{"id":"W2091349625","doi":"10.1016/s0014-5793(02)02470-5","title":"Extended longevity of <i>Caenorhabditis elegans</i> by knocking in extra copies of hsp70F, a homolog of mot‐2 (mortalin)/mthsp70/Grp75","year":2002,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":228,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Kanazawa University","keywords":"Caenorhabditis elegans; Longevity; Biology; Complementary DNA; clone (Java method); Hsp70; Life span; Molecular biology; Transgene; Cell biology; Gene; Heat shock protein; Genetics; Evolutionary biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007875455,0.0003346207,0.0001287428,0.0001630166,0.0001942995,0.0001837851,0.0001447809,0.0001715356,0.0009157551],"category_scores_gemma":[0.00005472834,0.0001146441,0.0001857641,0.00007043451,0.0001520668,0.0001324807,0.0001752457,0.000393397,0.0002856032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002769228,"about_ca_system_score_gemma":0.0001491929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008857838,"about_ca_topic_score_gemma":0.002219716,"domain_scores_codex":[0.9999529,0.000003445245,0.000006092728,0.00001326013,0.0000113838,0.00001299163],"domain_scores_gemma":[0.9999138,0.000008514005,0.00002434202,0.00001111456,0.00001005584,0.00003220558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003310804,0.000008356683,0.00008454621,0.00001382264,0.000002332804,0.00003970916,0.000005114207,0.00002034655,0.9992009,0.00004375187,0.00004422494,0.0005037212],"study_design_scores_gemma":[0.000021328,0.0002725892,0.01398865,0.00001490574,0.00002904151,0.0005607367,0.00002617638,0.0005777167,0.9795157,0.00006568441,0.004915759,0.00001158469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995327,0.0006180031,0.001233457,0.00007852633,0.00003170709,0.0000147955,0.000952539,0.0001131028,0.00163082],"genre_scores_gemma":[0.9910725,0.0006679012,0.002125232,0.00008272225,0.00001208827,0.00002998546,0.00149244,0.00006764955,0.004449434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009157551,"threshold_uncertainty_score":0.00306356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009098892435366825,"score_gpt":0.2064484940969027,"score_spread":0.1973496016615359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}