{"id":"W2091356687","doi":"10.1016/j.bioorg.2014.06.003","title":"Acyl transfer mechanisms of tissue transglutaminase","year":2014,"lang":"en","type":"review","venue":"Bioorganic Chemistry","topic":"Blood properties and coagulation","field":"Medicine","cited_by":103,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Tissue transglutaminase; Chemistry; Deamidation; Substrate (aquarium); Amine gas treating; Residue (chemistry); Biochemistry; Enzyme; Succinimide; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004288821,0.001100647,0.001100068,0.001403772,0.0002070959,0.0009624079,0.0007222607,0.0007835515,0.001624549],"category_scores_gemma":[0.0003719027,0.0002986772,0.0003848913,0.001762678,0.0005403395,0.001557789,0.0007756397,0.001440667,0.00155171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005915375,"about_ca_system_score_gemma":0.0007404566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00050699,"about_ca_topic_score_gemma":0.0007488507,"domain_scores_codex":[0.9998771,0.00001851174,0.00001750726,0.00002325656,0.00004549312,0.00001810729],"domain_scores_gemma":[0.999891,0.00004152422,0.00002285648,0.000005047644,0.00002813748,0.00001131012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001345316,0.00006997344,0.0001472784,0.01345101,0.0000827078,0.0003670726,0.00006527992,0.0007287257,0.01336354,0.007409017,0.01318879,0.9509921],"study_design_scores_gemma":[0.00002412602,0.0001010332,0.000447394,0.001257046,0.0001146171,0.001229091,0.00005044952,0.0002640073,0.004377553,0.00417921,0.9879309,0.00002470343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003335643,0.9972292,0.0005658227,0.0001797182,0.0002066387,0.000005357459,0.00001309875,0.000008587945,0.001458054],"genre_scores_gemma":[0.001463833,0.9968008,0.0003687252,0.0001012332,0.0001598251,0.000005248311,0.00002802527,0.000001452278,0.001070873],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001624549,"threshold_uncertainty_score":0.005434692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03205655448010158,"score_gpt":0.2868985409526411,"score_spread":0.2548419864725395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}