{"id":"W2091369988","doi":"10.1124/jpet.103.058792","title":"Mammalian Voltage-Gated Calcium Channels Are Potently Blocked by the Pyrethroid Insecticide Allethrin","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Pesticide Exposure and Toxicity","field":"Agricultural and Biological Sciences","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Sodium channel; Chemistry; Voltage-dependent calcium channel; Calcium; Pyrethroid; Biophysics; Calcium channel; Sodium; Pharmacology; Biochemistry; Biology; Pesticide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001977716,0.0002878832,0.0003015613,0.0001559256,0.0002105805,0.0002920289,0.0002520276,0.0004512026,0.002187166],"category_scores_gemma":[0.0003477747,0.0001711663,0.0002023882,0.0001490359,0.000350781,0.0002810238,0.0002056752,0.0007252134,0.0004843675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003113339,"about_ca_system_score_gemma":0.0003264056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006969493,"about_ca_topic_score_gemma":0.002229458,"domain_scores_codex":[0.9998134,0.00002362769,0.00001179486,0.00001912524,0.00006059144,0.00007156697],"domain_scores_gemma":[0.9998583,0.00004419141,0.00003984655,0.00001647191,0.00001487086,0.00002635158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003965617,0.00003936868,0.0001896355,0.00003926159,0.00001223,0.00008816958,0.00002447298,0.00005775678,0.9974322,0.0002120139,0.0001477874,0.001360474],"study_design_scores_gemma":[0.0001726566,0.0007154437,0.006817573,0.00001408755,0.00003640357,0.0004833897,0.00003386442,0.0008071549,0.9864386,0.0001386007,0.004335321,0.000006967542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921708,0.002347223,0.0009465254,0.0002802294,0.0000521418,0.00002675527,0.0001696798,0.0001030572,0.003903691],"genre_scores_gemma":[0.9933614,0.001883303,0.0006076686,0.0001273064,0.00002490715,0.00003502671,0.0004894079,0.00001548566,0.003455728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002187166,"threshold_uncertainty_score":0.007316768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03507088036500966,"score_gpt":0.2984829466410135,"score_spread":0.2634120662760038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}